A humanized antibody that binds to the interleukin 2 receptor (Q24600912)

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W P Schneider

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H E Selick

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P W Payne

4

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N F Landolfi

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J F Duncan

6

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N M Avdalovic

7

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R P Junghans

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T A Waldmann

Proceedings of the National Academy of Sciences of the United States of America

10

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language of work or name

English

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publication date

December 1989

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published in

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volume

86

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page(s)

10029-33

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issue

24

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Replacing the complementarity-determining regions in a human antibody with those from a mouse

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Reshaping human antibodies for therapy

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Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice

27 September 2017

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Chimeric mouse-human IgG1 antibody that can mediate lysis of cancer cells

27 September 2017

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Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex

27 September 2017

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Chimeric antibody with human constant regions and mouse variable regions directed against carcinoma-associated antigen 17-1A.

27 September 2017

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A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus

27 September 2017

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Effects of in-vivo administration of a monoclonal antibody specific for the interleukin-2 receptor on the acute graft-versus-host reaction in mice.

30 May 2018

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Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions

30 May 2018

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Therapy of patients with human T-cell lymphotrophic virus I-induced adult T-cell leukemia with anti-Tac, a monoclonal antibody to the receptor for interleukin-2.

30 May 2018

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Early experience with anti-Tac in clinical renal transplantation

30 May 2018

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A hapten-specific chimaeric IgE antibody with human physiological effector function.

30 May 2018

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Reshaping human antibodies: grafting an antilysozyme activity.

30 May 2018

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A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells

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12 December 2020

A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor

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Molecular dynamics of native protein. I. Computer simulation of trajectories

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Production of functional chimaeric mouse/human antibody

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Monoclonal antibody therapy. Anti-idiotypic and non-anti-idiotypic antibodies to OKT3 arising despite intense immunosuppression

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Synergism between immunoglobulin enhancers and promoters

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Anti-interleukin 2 receptor antibody suppresses murine diabetic insulitis and lupus nephritis

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REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H

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Prolongation of primate renal allograft survival by anti-Tac, an anti-human IL-2 receptor monoclonal antibody

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Expression in COS cells of a mouse-human chimaeric B72.3 antibody

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12 December 2020