Axonal α7 nicotinic ACh receptors modulate presynaptic NMDA receptor expression and structural plasticity of glutamatergic presynaptic boutons (Q24601769)

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English	Axonal α7 nicotinic ACh receptors modulate presynaptic NMDA receptor expression and structural plasticity of glutamatergic presynaptic boutons	scientific article

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13 February 2020

Axonal α7 nicotinic ACh receptors modulate presynaptic NMDA receptor expression and structural plasticity of glutamatergic presynaptic boutons (English)

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13 February 2020

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13 February 2020

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13 February 2020

Douglas A Coulter

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13 February 2020

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Hong Lin

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13 February 2020

Fu-Chun Hsu

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13 February 2020

Shachee Doshi

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13 February 2020

David R Lynch

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13 February 2020

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3 September 2010

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13 February 2020

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Proceedings of the National Academy of Sciences of the United States of America

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13 February 2020

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13 February 2020

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13 February 2020

16661-16666

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13 February 2020

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Desensitization of nicotinic acetylcholine receptors as a strategy for drug development

1 reference

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A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits

1 reference

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The glutamate receptor ion channels

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7 April 2017

Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease

1 reference

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Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease

1 reference

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Presynaptic type III neuregulin1-ErbB signaling targets {alpha}7 nicotinic acetylcholine receptors to axons

1 reference

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Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory

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Organization of NMDA receptors at extrasynaptic locations

1 reference

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A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia

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alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment

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27 September 2017

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Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors

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Structural plasticity of axon terminals in the adult

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Formation of presynaptic terminals at predefined sites along axons.

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Facilitation of glutamatergic neurotransmission by presynaptic nicotinic acetylcholine receptors

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Relationship between the increased cell surface alpha7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists

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Inactivation of alpha7 ACh receptors and activation of non-alpha7 ACh receptors both contribute to long term potentiation induction in the hippocampal CA1 region.

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Nicotine selectively enhances NMDA receptor-mediated synaptic transmission during postnatal development in sensory neocortex.

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21 January 2018

Nicotinic acetylcholine receptors at glutamate synapses facilitate long-term depression or potentiation.

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1 reference

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21 January 2018

Nicotine exposure in vivo induces long-lasting enhancement of NMDA receptor-mediated currents in the hippocampus.

1 reference

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21 January 2018

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1 reference

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21 January 2018

Genetic variation in the alpha 7 nicotinic acetylcholine receptor is associated with delusional symptoms in Alzheimer's disease

1 reference

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Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21.

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20817852

12 December 2020

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10.1073/PNAS.1007397107

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13 February 2020

2010PNAS..10716661L

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13 February 2020

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13 February 2020

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