Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42 (Q24603554)

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K F Tolias

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C L Carpenter

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F S Rosen

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T Kirchhausen

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

28 May 1996

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published in

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volume

93

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issue

11

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page(s)

5615-8

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cites work

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

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A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

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Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

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Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

7 April 2017

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

7 April 2017

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Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

7 April 2017

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

7 April 2017

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Small GTP-binding proteins and the regulation of the actin cytoskeleton

7 April 2017

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Eczema associated with thrombocytopenic purpura and purulent otitis media; report of five fatal cases.

7 April 2017

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Pedigree demonstrating a sex-linked recessive condition characterized by draining ears, eczematoid dermatitis and bloody diarrhea.

27 September 2017

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Defects in Wiskott-Aldrich syndrome blood cells

27 September 2017

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Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus

27 September 2017

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T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses.

27 September 2017

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Regulation and function of the Rho subfamily of small GTPases

27 September 2017

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A multiinstitutional survey of the Wiskott-Aldrich syndrome.

27 September 2017

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Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

27 September 2017

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Identification of mutations in the Wiskott-Aldrich syndrome gene and characterization of a polymorphic dinucleotide repeat at DXS6940, adjacent to the disease gene

27 September 2017

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Rho family GTPases bind to phosphoinositide kinases

27 September 2017

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Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions

27 September 2017

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Wiskott-Aldrich syndrome. An immunologic deficiency disease involving the afferent limb of immunity

27 September 2017

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Cell biology of cytotoxic and helper T cell functions: immunofluorescence microscopic studies of single cells and cell couples

27 September 2017

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T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome

27 September 2017

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Antigen-receptor complex stimulation triggers protein kinase C-dependent CD11a/CD18-cytoskeleton association in T lymphocytes

27 September 2017

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Spatial relationships of microtubule-organizing centers and the contact area of cytotoxic T lymphocytes and target cells

27 September 2017

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The Wiskott-Aldrich syndrome. A disorder with a possible defect in antigen processing or recognition.

27 September 2017

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The Wiskott-Aldrich syndrome: refinement of the localization on Xp and identification of another closely linked marker locus, OATL1

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39296

Dichotomy of antibody response to group A streptococcal antigens in Wiskott-Aldrich syndrome

30 May 2018

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12 December 2020

The Wiskott-Aldrich syndrome: studies of lymphocytes, granulocytes, and platelets

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12 December 2020

Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome

1 reference

12 December 2020

Close linkage of hypervariable marker DXS255 to disease locus of Wiskott-Aldrich syndrome

1 reference

12 December 2020

Localization of the gene for the Wiskott-Aldrich syndrome between two flanking markers, TIMP and DXS255, on Xp11.22–Xp11.3

1 reference

12 December 2020

Actin polymerization and pseudopod reorganization accompany anti-CD3-induced growth arrest in Jurkat T cells

1 reference

12 December 2020