Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation (Q24603636)

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P Castella

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J Rockwood

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J Wagner

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M Caudy

Molecular interaction between TLE1 and the carboxyl-terminal domain of HES-1 containing the WRPW motif

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language of work or name

English

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publication date

1 December 1997

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published in

Genes & Development

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volume

11

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issue

23

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page(s)

3168-81

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cites work

1 reference

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Functional gene cassettes in development

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Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements

7 April 2017

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REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons

7 April 2017

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

7 April 2017

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

7 April 2017

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The signal-dependent coactivator CBP is a nuclear target for pp90RSK

7 April 2017

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Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

7 April 2017

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Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects

7 April 2017

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Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

7 April 2017

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Signalling downstream of activated mammalian Notch

7 April 2017

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The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

7 April 2017

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The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain

7 April 2017

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Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split

7 April 2017

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The MyoD family and myogenesis: redundancy, networks, and thresholds

7 April 2017

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Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

7 April 2017

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

7 April 2017

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Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression

7 April 2017

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Intracellular signaling pathways activated by neurotrophic factors

27 September 2017

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Silencing is golden: negative regulation in the control of neuronal gene transcription

27 September 2017

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A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation

27 September 2017

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Helix-loop-helix proteins as regulators of muscle-specific transcription.

27 September 2017

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Predicting protein function: a versatile tool for the Apple Macintosh

27 September 2017

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Involvement of JunD in transcriptional activation of the orphan receptor gene nur77 by nerve growth factor and membrane depolarization in PC12 cells

27 September 2017

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Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system.

27 September 2017

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Neurotrophin signal transduction by the Trk receptor

27 September 2017

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Neurotrophic factors and synaptic plasticity

27 September 2017

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Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells

27 September 2017

1 reference

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The Drosophila hairy protein acts in both segmentation and bristle patterning and shows homology to N-myc

27 September 2017

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Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins

27 September 2017

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Genes required for specifying cell fates in Drosophila embryonic sensory nervous system

27 September 2017

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Enhancer of splitD, a dominant mutation of Drosophila, and its use in the study of functional domains of a helix-loop-helix protein

27 September 2017

1 reference

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The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins

27 September 2017

1 reference

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Patterning of the Drosophila nervous system: the achaete-scute gene complex

27 September 2017

1 reference

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Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316755

FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains

27 September 2017

1 reference

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The function of hairy-related bHLH repressor proteins in cell fate decisions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316755

bHLH proteins encoded by the Enhancer of split complex of Drosophila negatively interfere with transcriptional activation mediated by proneural genes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316755

Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316755

Differential expression of PKC isoforms and PC12 cell differentiation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316755

Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316755

Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316755

Nerve growth factor-induced neuronal differentiation of PC12 pheochromocytoma cells: lack of inhibition by a tumor promoter.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316755

Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-zeta isoform

28 November 2018

1 reference

12 December 2020

Changes of Nuclear Protein Kinase C Activity and Isotype Composition in PC12 Cell Proliferation and Differentiation

1 reference

12 December 2020

Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis

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12 December 2020

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

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12 December 2020

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells

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12 December 2020

Identifiers

DOI

10.1101/GAD.11.23.3168

1 reference

4761815

4761815

1 reference

1 reference

1 reference