Neonatal mouse-derived engineered cardiac tissue: a novel model system for studying genetic heart disease (Q24605124)

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A C Grimes

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C W Tong

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T M Brost

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R L Moss

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J C Ralphe

Loaded shortening, power output, and rate of force redevelopment are increased with knockout of cardiac myosin binding protein-C

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language of work or name

English

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publication date

24 June 2011

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published in

Circulation Research

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volume

109

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issue

1

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page(s)

8-19

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cites work

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Evidence from human myectomy samples that MYBPC3 mutations cause hypertrophic cardiomyopathy through haploinsufficiency

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Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

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In vivo left ventricular functional capacity is compromised in cMyBP-C null mice

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Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure

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Scaffolds with covalently immobilized VEGF and Angiopoietin-1 for vascularization of engineered tissues

27 September 2017

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27 September 2017

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Accordion-like honeycombs for tissue engineering of cardiac anisotropy

27 September 2017

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Acceleration of crossbridge kinetics by protein kinase A phosphorylation of cardiac myosin binding protein C modulates cardiac function.

27 September 2017

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Pulsatile myocardial tubes fabricated with cell sheet engineering

27 September 2017

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Reconstitution of the Frank-Starling mechanism in engineered heart tissues

27 September 2017

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Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds

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Neonatal rat cardiomyocytes--a model for the study of morphological, biochemical and electrophysiological characteristics of the heart.

27 September 2017

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Cardiac tissue engineering

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Three-dimensional engineered heart tissue from neonatal rat cardiac myocytes

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Force and velocity of sarcomere shortening in trabeculae from rat heart. Effects of temperature

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Composite cell sheets: a further step toward safe and effective myocardial regeneration by cardiac progenitors derived from embryonic stem cells.

27 September 2017

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Development of a drug screening platform based on engineered heart tissue

30 May 2018

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Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells.

28 November 2018

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Neonatal murine heart slices. A robust model to study ventricular isometric contractions

28 November 2018

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Engineered cardiac tissues for in vitro assessment of contractile function and repair mechanisms.

28 November 2018

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Contractile three-dimensional bioengineered heart muscle for myocardial regeneration.

28 November 2018

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Optimizing engineered heart tissue for therapeutic applications as surrogate heart muscle.

28 November 2018

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Engineered early embryonic cardiac tissue retains proliferative and contractile properties of developing embryonic myocardium.

28 November 2018

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Oxygen gradients correlate with cell density and cell viability in engineered cardiac tissue.

28 November 2018

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Roles of phosphorylation of myosin binding protein-C and troponin I in mouse cardiac muscle twitch dynamics.

28 November 2018

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Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces

28 November 2018

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Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat.

28 November 2018

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Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization.

28 November 2018

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Effect of ryanodine on neonatal and adult rat heart: developmental increase in sarcoplasmic reticulum function.

28 November 2018

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Chronotropic responsiveness of developing sinoatrial and ventricular rat myocytes to autonomic agonists following adrenergic and cholinergic innervation in vitro

28 November 2018

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12 December 2020

Sympathetic innervation improves the contractile performance of neonatal cardiac ventricular myocytes in culture

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12 December 2020

Three-dimensional reconstitution of embryonic cardiomyocytes in a collagen matrix: a new heart muscle model system

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12 December 2020

Ablation of cardiac myosin-binding protein-C accelerates stretch activation in murine skinned myocardium

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12 December 2020

Protein kinase A-mediated acceleration of the stretch activation response in murine skinned myocardium is eliminated by ablation of cMyBP-C

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12 December 2020

Differential roles of cardiac myosin-binding protein C and cardiac troponin I in the myofibrillar force responses to protein kinase A phosphorylation

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12 December 2020

Prevalence of sarcomere protein gene mutations in preadolescent children with hypertrophic cardiomyopathy

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12 December 2020