Development of a second-generation antiandrogen for treatment of advanced prostate cancer (Q24605577)

1

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Samedy Ouk

2

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Nicola J Clegg

3

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Yu Chen

4

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Philip A Watson

5

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John Wongvipat

7

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Peter M Smith-Jones

8

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Dongwon Yoo

9

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Andrew Kwon

10

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Teresa Wasielewska

11

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Derek Welsbie

12

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Charlie Degui Chen

13

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Celestia S Higano

14

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Tomasz M Beer

15

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David T Hung

16

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Howard I Scher

17

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Michael E Jung

18

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Charles L Sawyers

Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells

19

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language of work or name

English

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publication date

8 May 2009

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published in

Science

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volume

324

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issue

5928

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page(s)

787-90

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Structural basis for antagonism and resistance of bicalutamide in prostate cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Molecular determinants of resistance to antiandrogen therapy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Androgen receptor: a key molecule in the progression of prostate cancer to hormone independence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Design, synthesis, and pharmacological characterization of 4-[4, 4-dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl]- 2-iodobenzonitrile as a high-affinity nonsteroidal androgen receptor ligand

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Non-steroidal antiandrogens: synthesis and biological profile of high-affinity ligands for the androgen receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1168175

Transgenic mouse model for rapid pharmacodynamic evaluation of antiandrogens

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1168175

Tumor localization of 16beta-18F-fluoro-5alpha-dihydrotestosterone versus 18F-FDG in patients with progressive, metastatic prostate cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2981508

Steroid hormone withdrawal syndromes. Pathophysiology and clinical significance

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19359544

12 December 2020

inferred from PubMed ID database lookup

Receptor affinity and potency of non-steroidal antiandrogens: translation of preclinical findings into clinical activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19359544

12 December 2020

inferred from PubMed ID database lookup

The pharmacokinetics of Casodex in prostate cancer patients after single and during multiple dosing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19359544

12 December 2020

inferred from PubMed ID database lookup

Advanced prostatic cancer: clinical and hormonal response to flutamide in patients pretreated with LHRH analogue and cyproterone acetate

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1168175

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1126/SCIENCE.1168175

1 reference

309044

309044

1 reference

1 reference

1 reference