Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation (Q24606703)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20233866%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20233866%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

1 reference

1

1 reference

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19 January 2020

author name string

Bachchu Lal

2

1 reference

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19 January 2020

Xin Zhou

3

1 reference

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19 January 2020

Sandra Ho

4

1 reference

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19 January 2020

Shuli Xia

5

1 reference

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19 January 2020

Alexandra Taeger

6

1 reference

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19 January 2020

Jamie Murray

7

1 reference

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19 January 2020

John Laterra

8

1 reference

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19 January 2020

language of work or name

English

0 references

publication date

16 March 2010

1 reference

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19 January 2020

1 reference

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19 January 2020

volume

70

1 reference

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19 January 2020

issue

7

1 reference

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19 January 2020

page(s)

2932-2941

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describes a project that uses

19 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2848876/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway

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CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

7 April 2017

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7 April 2017

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Regulation of c-Met-dependent gene expression by PTEN

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Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3)

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848876

Cyr61, product of a growth factor-inducible immediate-early gene, regulates chondrogenesis in mouse limb bud mesenchymal cells

7 April 2017

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Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with Nanog.

7 April 2017

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Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis

27 September 2017

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Functional domains of CCN1 (Cyr61) regulate breast cancer progression.

27 September 2017

1 reference

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Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor

27 September 2017

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NK4, an antagonist of hepatocyte growth factor (HGF), inhibits growth of multiple myeloma cells: molecular targeting of angiogenic growth factor.

27 September 2017

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Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts

27 September 2017

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Activation of AKT kinases in cancer: implications for therapeutic targeting

27 September 2017

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Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation

27 September 2017

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A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway.

27 September 2017

1 reference

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Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G(1) is c-Myc dependent and independent of p27 suppression, Cdk2 activation, or E2F1-dependent transcription

27 September 2017

1 reference

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Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.

27 September 2017

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Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease

27 September 2017

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Expression and function of CYR61, an angiogenic factor, in breast cancer cell lines and tumor biopsies.

27 September 2017

1 reference

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Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans

27 September 2017

1 reference

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Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas

27 September 2017

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Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3.

27 September 2017

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Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells

27 September 2017

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Met and hepatocyte growth factor/scatter factor expression in human gliomas

27 September 2017

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Scatter factor/hepatocyte growth factor expression enhances human glioblastoma tumorigenicity and growth

27 September 2017

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Increased expression of CYR61, an extracellular matrix signaling protein, in human benign prostatic hyperplasia and its regulation by lysophosphatidic acid

27 September 2017

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Cyr61, a member of the CCN family, is required for MCF-7 cell proliferation: regulation by 17beta-estradiol and overexpression in human breast cancer

30 May 2018

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Determination of subcutaneous tumor size in athymic (nude) mice

30 May 2018

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Characterization of monoclonal antibodies to two Treponema denticola serotypes by the indirect fluorescent-antibody assay

30 May 2018

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A Key role for cyclic AMP-responsive element binding protein in hypoxia-mediated activation of the angiogenesis factor CCN1 (CYR61) in Tumor cells

30 May 2018

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CYR61: a new measure of lung cancer outcome

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848876

Contrasting role of phospholipase C-gamma1 in the expression of immediate early genes induced by epidermal or platelet-derived growth factors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848876

Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848876

Cyr61 is overexpressed in gliomas and involved in integrin-linked kinase-mediated Akt and beta-catenin-TCF/Lef signaling pathways.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848876

alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848876

Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848876

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20233866

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-09-3570

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20233866%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20233866%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2 references