The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis (Q24608044)

2

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C Chen

3

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J Bash

4

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C Gélinas

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

5

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language of work or name

English

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publication date

15 February 1999

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published in

Genes & Development

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volume

13

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issue

4

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page(s)

382-7

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cites work

1 reference

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Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1

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Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2

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A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow

7 April 2017

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The Bcl-2 protein family: arbiters of cell survival

7 April 2017

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

7 April 2017

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

7 April 2017

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

7 April 2017

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

7 April 2017

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

7 April 2017

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Rel blocks both anti-Fas- and TNF alpha-induced apoptosis and an intact Rel transactivation domain is essential for this effect

7 April 2017

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ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein

27 September 2017

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c-Rel arrests the proliferation of HeLa cells and affects critical regulators of the G1/S-phase transition

27 September 2017

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

27 September 2017

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Human A1, a Bcl-2-related gene, is induced in leukemic cells by cytokines as well as differentiating factors

27 September 2017

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Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells

27 September 2017

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Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB.

27 September 2017

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Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation

27 September 2017

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Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

27 September 2017

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Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements

27 September 2017

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The 19-Kilodalton Adenovirus E1B Transforming Protein Inhibits Programmed Cell Death and Prevents Cytolysis by Tumor Necrosis Factor α

27 September 2017

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Mechanisms of Bcl-2 family protein function and dysfunction in health and disease

27 September 2017

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A1, a Bcl-2 family member, prolongs cell survival and permits myeloid differentiation.

27 September 2017

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Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation

27 September 2017

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The v-Rel oncoprotein blocks apoptosis and proteolysis of I kappa B-alpha in transformed chicken spleen cells

27 September 2017

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Rel/NF-kappa B transcription factors and the control of apoptosis

27 September 2017

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bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity

30 May 2018

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Developmental expression of the mouse c-rel proto-oncogene in hematopoietic organs.

30 May 2018

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Inhibition of TNF-induced apoptosis by NF-kappa B.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316475

Expression of Bfl-1 in normal and tumor tissues: Bfl-1 overexpression in cancer is attributable to its preferential expression in infiltrating inflammatory cells.

28 November 2018

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IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10049353

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

v-Rel prevents apoptosis in transformed lymphoid cells and blocks TNFalpha-induced cell death

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10049353

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.13.4.382

1 reference

827265

827265

1 reference

1 reference

1 reference