Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeutics (Q24608073)

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

Europe PubMed Central

title

Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeutics (English)

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2

Daniel R Weinberger

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author name string

Catherine M Diaz-Asper

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1

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Terry E Goldberg

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3

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language of work or name

English

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publication date

January 2006

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issue

1

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page(s)

97-105

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cites work

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Catechol O -methyltransferase val 158 -met genotype and individual variation in the brain response to amphetamine

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Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase

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Catechol-O-methyltransferase val108/158met genotype predicts working memory response to antipsychotic medications

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Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing

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Catechol O-methyltransferase inhibitor tolcapone has minor influence on performance in experimental memory models in rats

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Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters

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Variants in the catechol-o-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families

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A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition

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New evidence of association between COMT gene and prefrontal neurocognitive function in healthy individuals from sibling pairs discordant for psychosis

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Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility.

21 January 2018

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Effect of COMT Val158Met polymorphism on the Continuous Performance Test, Identical Pairs Version: tuning rather than improving performance

21 January 2018

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Cognitive improvement during Tolcapone treatment in Parkinson's disease.

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18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease

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A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain

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Population variation in linkage disequilibrium across the COMT gene considering promoter region and coding region variation

21 January 2018

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3-Methoxytyramine Is the Major Metabolite of Released Dopamine in the Rat Frontal Cortex: Reassessment of the Effects of Antipsychotics on the Dynamics of Dopamine Release and Metabolism in the Frontal Cortex, Nucleus Accumbens, and Striatum by a Sim

21 January 2018

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Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11

21 January 2018

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Interaction of COMT (Val(108/158)Met) genotype and olanzapine treatment on prefrontal cortical function in patients with schizophrenia.

21 January 2018

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Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter.

28 November 2018

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Tolcapone, an inhibitor of catechol: O-methyltransferase, counteracts memory deficits caused by bilateral cholinotoxin lesions of the basal nuclei of Meynert

28 November 2018

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Wisconsin Card Sorting Test: an indicator of vulnerability to schizophrenia?

28 November 2018

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12 December 2020

Patterns of neuropsychological deficits that discriminate schizophrenic individuals from siblings and control subjects

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12 December 2020

Preferential transmission of the high activity allele of COMT in schizophrenia

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12 December 2020

Catechol-O-methyltransferase polymorphisms and schizophrenia: a transmission disequilibrium study in multiply affected families

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12 December 2020

The differential clinical and neurocognitive profiles of COMT SNP rs165599 genotypes in schizophrenia

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12 December 2020

Catechol-O-methyltransferase Val-108/158-Met gene variants associated with performance on the Wisconsin Card Sorting Test

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12 December 2020

Haplotype relative risk study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD): Association of the high-enzyme activity val allele with adhd impulsive-hyperactive phenotype

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURX.2005.12.010

7 January 2021

inferred from DOI database lookup

Interaction of COMT Val108/158 Met Genotype and Olanzapine Treatment on Prefrontal Cortical Function in Patients With Schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURX.2005.12.010

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.NURX.2005.12.010

1 reference

1 reference

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PubMed publication ID

16490416

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