Molecular subgroups of medulloblastoma: the current consensus (Q24615271)

Stefan M Pfister

16

0 references

Peter Lichter

12

Peter Lichter

0 references

Charles G Eberhart

7

Charles G Eberhart

0 references

Stefan Rutkowski

9

Stefan Rutkowski

0 references

Marcel Kool

15

Marcel Kool

0 references

Paul A Northcott

2

Paul A Northcott

0 references

Andrey Korshunov

3

Andrey Korshunov

0 references

Michael D. Taylor

1

Michael D Taylor

0 references

Scott L Pomeroy

14

Scott L Pomeroy

0 references

Richard Gilbertson

13

Richard J Gilbertson

0 references

Yoon-Jae Cho

5

Yoon-Jae Cho

0 references

Steven Clifford

6

Steven C Clifford

0 references

Amar Gajjar

10

Amar Gajjar

0 references

author name string

D Williams Parsons

8

0 references

David W Ellison

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

11

0 references

language of work or name

English

0 references

publication date

April 2012

0 references

published in

Acta Neuropathologica

0 references

volume

123

0 references

issue

4

0 references

page(s)

465-72

0 references

cites work

1 reference

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7 April 2017

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7 April 2017

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Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

7 April 2017

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Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

7 April 2017

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Development and cancer of the cerebellum

7 April 2017

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The genetic landscape of the childhood cancer medulloblastoma

7 April 2017

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Subtypes of medulloblastoma have distinct developmental origins

7 April 2017

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Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

7 April 2017

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Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

7 April 2017

1 reference

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beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee

7 April 2017

1 reference

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Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

7 April 2017

1 reference

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Prediction of central nervous system embryonal tumour outcome based on gene expression

7 April 2017

1 reference

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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

7 April 2017

1 reference

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Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

7 April 2017

1 reference

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FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma

27 September 2017

1 reference

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Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

27 September 2017

1 reference

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Rapid diagnosis of medulloblastoma molecular subgroups

27 September 2017

1 reference

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Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

27 September 2017

1 reference

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Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables

27 September 2017

1 reference

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Medulloblastoma comprises four distinct molecular variants

27 September 2017

1 reference

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A pathway-based classification of human breast cancer.

27 September 2017

1 reference

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An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

OTX1 and OTX2 expression correlates with the clinicopathologic classification of medulloblastomas

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Distinctive clinical course and pattern of relapse in adolescents with medulloblastoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Medulloblastoma in the second decade of life: a specific group with respect to toxicity and management: a Canadian Pediatric Brain Tumor Consortium Study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Mutations in SUFU predispose to medulloblastoma

27 September 2017

1 reference

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Molecular insight into medulloblastoma and central nervous system primitive neuroectodermal tumor biology from hereditary syndromes: a review

27 September 2017

1 reference

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The molecular basis of Turcot's syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Patching together the genetics of Gorlin syndrome

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma.

30 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Central and extrapontine myelinolysis: then...and now.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Nodule formation and desmoplasia in medulloblastomas-defining the nodular/desmoplastic variant and its biological behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Identification of a SUFU germline mutation in a family with Gorlin syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Adult medulloblastoma comprises three major molecular variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Heterogeneity of familial medulloblastoma and contribution of germline PTCH1 and SUFU mutations to sporadic medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0922-Z

Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Sporadic medulloblastomas contain oncogenic beta-catenin mutations.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306779

Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22134537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Incomplete penetrance of the predisposition to medulloblastoma associated with germ-line SUFU mutations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22134537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00401-011-0922-Z

1 reference

Dimensions Publication ID

85166

1012707701

0 references

85166

1 reference

1 reference

1 reference