Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells (Q24615775)

GOA release 2020-03-11

author

Philippa Marrack

8

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John Kappler

7

object named as

John Kappler

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Megan Macleod

3

object named as

Megan K L MacLeod

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Baoli Yang

1

object named as

Baoli Yang

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author name string

Denise L Gay

2

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Xiao Cao

4

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Tamara Hala

5

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Eileen M Sweezer

6

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Paula M Oliver

Nedd4 controls animal growth by regulating IGF-1 signaling

9

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language of work or name

English

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publication date

December 2008

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published in

Nature Immunology

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volume

9

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page(s)

1356-63

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issue

12

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cites work

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Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation

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WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation

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27 September 2017

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An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

27 September 2017

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Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence

30 May 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNI.1670

Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation

21 January 2018

1 reference

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The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells

28 November 2018

1 reference

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Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935464

Notch activity influences the alphabeta versus gammadelta T cell lineage decision

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935464

Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935464

Absence of B7-dependent responses in CD28-deficient mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935464

Molecular regulation of interleukin-2 expression by CD28 co-stimulation and anergy

28 November 2018

1 reference

12 December 2020

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

12 December 2020

Cutting edge: T cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN

1 reference

12 December 2020

Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death

1 reference

12 December 2020

Cutting Edge: Regulation of T Cell Activation Threshold by CD28 Costimulation Through Targeting Cbl-b for Ubiquitination

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.1670

1 reference

2260532

2260532

1 reference

1 reference

1 reference