Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? (Q24617857)

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Hyoung Tae Kim

2

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Lily Ting

3

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Alfred L Goldberg

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

5

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language of work or name

English

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publication date

20 February 2013

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published in

The EMBO Journal

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volume

32

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issue

4

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page(s)

552-65

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cites work

1 reference

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VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo

7 April 2017

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Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

7 April 2017

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K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

7 April 2017

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7 April 2017

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Evidence for distinct functions for human DNA repair factors hHR23A and hHR23B

7 April 2017

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Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway

7 April 2017

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Endofin Recruits TOM1 to Endosomes

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Tom1, a VHS Domain-containing Protein, Interacts with Tollip, Ubiquitin, and Clathrin

7 April 2017

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Rad23 ubiquitin-associated domains (UBA) inhibit 26 S proteasome-catalyzed proteolysis by sequestering lysine 48-linked polyubiquitin chains

7 April 2017

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A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

7 April 2017

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Recognition of the polyubiquitin proteolytic signal

7 April 2017

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Hybrid Structural Model of the Complete Human ESCRT-0 Complex

7 April 2017

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Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

7 April 2017

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Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction

7 April 2017

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Proteasome subunit Rpn13 is a novel ubiquitin receptor

7 April 2017

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Mechanisms underlying ubiquitination

7 April 2017

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7 April 2017

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Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

7 April 2017

1 reference

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Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system

7 April 2017

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Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome

7 April 2017

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Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B

7 April 2017

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Recognition and processing of ubiquitin-protein conjugates by the proteasome

7 April 2017

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Enhancement of proteasome activity by a small-molecule inhibitor of USP14

7 April 2017

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The emerging shape of the ESCRT machinery

7 April 2017

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Ubiquitin-binding domains

7 April 2017

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How ubiquitin functions with ESCRTs

7 April 2017

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Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease

27 September 2017

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The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome

27 September 2017

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27 September 2017

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Principles of ubiquitin and SUMO modifications in DNA repair.

27 September 2017

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The trafficking and regulation of membrane receptors by the RING-CH ubiquitin E3 ligases.

27 September 2017

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The specificities of Kaposi's sarcoma-associated herpesvirus-encoded E3 ubiquitin ligases are determined by the positions of lysine or cysteine residues within the intracytoplasmic domains of their targets

27 September 2017

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Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

27 September 2017

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Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of HHR23A.

27 September 2017

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Rad23 promotes the targeting of proteolytic substrates to the proteasome

27 September 2017

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Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation

27 September 2017

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Macromolecular crowding: obvious but underappreciated

27 September 2017

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Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination.

27 September 2017

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ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradation

27 September 2017

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Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening

30 May 2018

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S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains

30 May 2018

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Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

30 May 2018

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Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins

30 May 2018

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Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules

28 November 2018

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Studies on the intracellular localization of hHR23B.

28 November 2018

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Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain

28 November 2018

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Relative levels of the two mammalian Rad23 homologs determine composition and stability of the xeroderma pigmentosum group C protein complex.

28 November 2018

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In vitro assembly and recognition of Lys-63 polyubiquitin chains

28 November 2018

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Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6)

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23314748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23314748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proteasome inhibition measurements: clinical application

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23314748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2012.354

1 reference

1 reference

1 reference

PubMed publication ID

23314748

1 reference