Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 Asn-->Asp) (Q24617877)

2

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J Y Borg

3

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R W Carrell

4

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M R Wardell

Journal of Clinical Investigation

5

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language of work or name

English

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publication date

December 1994

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published in

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volume

94

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issue

6

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page(s)

2265-74

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Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins

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A hinge region mutation in C1-inhibitor (Ala436-->Thr) results in nonsubstrate-like behavior and in polymerization of the molecule.

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Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

27 September 2017

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Serpin tertiary structure transformation

27 September 2017

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27 September 2017

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The Size and Shape of Human and Bovine Antithrombin III

27 September 2017

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30 May 2018

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The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor

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Structural basis of latency in plasminogen activator inhibitor-1

30 May 2018

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Crystallization and Preliminary X-ray Diffraction Analysis of Two Conformations of Intact Human Antithrombin

19 June 2018

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Crystal structure of plakalbumin, a proteolytically nicked form of ovalbumin. Its relationship to the structure of cleaved alpha-1-proteinase inhibitor

28 November 2018

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Antithrombin Cambridge, 384 Ala to Pro: a new variant identified using the polymerase chain reaction

28 November 2018

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12 December 2020

Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmi

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12 December 2020

Mobile reactive centre of serpins and the control of thrombosis

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12 December 2020

Effect of the Z mutation on the physical and inhibitory properties of alpha 1-antitrypsin

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12 December 2020

Alpha 1-antitrypsin Siiyama (Ser53-->Phe). Further evidence for intracellular loop-sheet polymerization

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12 December 2020

C1 inhibitor mutations which affect intracellular transport and secretion in type I hereditary angioedema

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12 December 2020

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12 December 2020

Binding of low-affinity and high-affinity heparin to antithrombin. Ultraviolet difference spectroscopy and circular dichroism studies

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12 December 2020

A simple two-step procedure for the isolation of antithrombin III from biological fluids

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12 December 2020

Conformation of the reactive site loop of alpha 1-proteinase inhibitor probed by limited proteolysis

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12 December 2020

Characterization of the heparin-binding site of glia-derived nexin/protease nexin-1

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12 December 2020

Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

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12 December 2020