Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers (Q24620129)

ORCID Public Data File 2021

Paolo Lusso

7

object named as

Paolo Lusso

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author name string

Massimiliano Secchi

2

0 references

Xiaowen Liu

3

0 references

Angela Bachi

4

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Letong Jia

5

0 references

Qiang Xu

Antimicrobial Agents and Chemotherapy

6

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language of work or name

English

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publication date

July 2010

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published in

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volume

54

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issue

7

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page(s)

2994-3001

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cites work

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Structural and functional studies of the potent anti-HIV chemokine variant P2-RANTES

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The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity

7 April 2017

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Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

7 April 2017

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Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

7 April 2017

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Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

7 April 2017

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The superior folding of a RANTES analogue expressed in lactobacilli as compared to mammalian cells reveals a promising system to screen new RANTES mutants.

7 April 2017

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A Chinese rhesus macaque (Macaca mulatta) model for vaginal Lactobacillus colonization and live microbicide development

27 September 2017

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Macrophages in vaginal but not intestinal mucosa are monocyte-like and permissive to human immunodeficiency virus type 1 infection

27 September 2017

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Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide

27 September 2017

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Vaginal microbicides and the prevention of HIV transmission

27 September 2017

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Vaginal microbicides: where are we and where are we going?

27 September 2017

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CCL5 regulation of mucosal chlamydial immunity and infection

27 September 2017

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Engineering of a human vaginal Lactobacillus strain for surface expression of two-domain CD4 molecules

27 September 2017

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Probiotics: potential to prevent HIV and sexually transmitted infections in women

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Rational design of novel HIV-1 entry inhibitors by RANTES engineering

27 September 2017

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Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.

27 September 2017

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Susceptibility of CCR5-deficient mice to genital herpes simplex virus type 2 is linked to NK cell mobilization

27 September 2017

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Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N

27 September 2017

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Activity of HIV entry and fusion inhibitors expressed by the human vaginal colonizing probiotic Lactobacillus reuteri RC-14.

27 September 2017

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Bioengineering lactic acid bacteria to secrete the HIV-1 virucide cyanovirin

27 September 2017

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An anti-HIV microbicide comes alive

27 September 2017

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Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

27 September 2017

1 reference

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Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897324

Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTES

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897324

Enhancement of the HIV-1 inhibitory activity of RANTES by modification of the N-terminal region: dissociation from CCR5 activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897324

Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development

27 September 2017

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Divergence in codon usage of Lactobacillus species

27 September 2017

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Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1.

27 September 2017

1 reference

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The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897324

An anti-HIV microbicide engineered in commensal bacteria: secretion of HIV-1 fusion inhibitors by lactobacilli.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897324

Lactobacilli-expressed single-chain variable fragment (scFv) specific for intercellular adhesion molecule 1 (ICAM-1) blocks cell-associated HIV-1 transmission across a cervical epithelial monolayer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897324

Genital tract shedding of herpes simplex virus type 2 in women: effects of hormonal contraception, bacterial vaginosis, and vaginal group B Streptococcus colonization

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897324

The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897324

Analysis of the interaction between the HIV-inactivating protein cyanovirin-N and soluble forms of the envelope glycoproteins gp120 and gp41

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20479208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Bacterial vaginosis and disturbances of vaginal flora: association with increased acquisition of HIV

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20479208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Bacterial vaginosis and disturbances of vaginal flora

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FAAC.01492-09