Fate mapping of IL-17-producing T cells in inflammatory responses (Q24621244)

13

Brigitta Stockinger

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Christoph Wilhelm

Christoph Wilhelm

8

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Alexandre J. Potocnik

Alexandre J Potocnik

12

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Marc Veldhoen

Marc Veldhoen

3

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Helena Ahlfors

Helena Ahlfors

7

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Keiji Hirota

Keiji Hirota

1

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author name string

Eve Hornsby

4

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Ying Li

5

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Daniel J Cua

6

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Mauro Tolaini

9

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Ursula Menzel

10

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Anna Garefalaki

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

11

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language of work or name

English

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publication date

March 2011

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published in

Nature Immunology

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volume

12

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issue

3

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page(s)

255-63

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cites work

1 reference

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7 April 2017

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The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

7 April 2017

1 reference

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Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

7 April 2017

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Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

7 April 2017

1 reference

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

7 April 2017

1 reference

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

7 April 2017

1 reference

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

7 April 2017

1 reference

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Codon-improved Cre recombinase (iCre) expression in the mouse

7 April 2017

1 reference

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Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

7 April 2017

1 reference

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

7 April 2017

1 reference

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Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

7 April 2017

1 reference

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Phenotypic and functional features of human Th17 cells

7 April 2017

1 reference

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The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

7 April 2017

1 reference

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Effector T cell plasticity: flexibility in the face of changing circumstances

27 September 2017

1 reference

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T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis

27 September 2017

1 reference

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Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

27 September 2017

1 reference

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Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

27 September 2017

1 reference

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Development, regulation and functional capacities of Th17 cells

27 September 2017

1 reference

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Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells

27 September 2017

1 reference

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Plasticity of CD4+ T cell lineage differentiation.

27 September 2017

1 reference

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IL-17F: regulation, signaling and function in inflammation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Late developmental plasticity in the T helper 17 lineage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Regional CNS responses to IFN-gamma determine lesion localization patterns during EAE pathogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

A rush to judgment on Th17

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Cutting edge: central nervous system plasmacytoid dendritic cells regulate the severity of relapsing experimental autoimmune encephalomyelitis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Th17 cell differentiation: the long and winding road

27 September 2017

1 reference

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Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

27 September 2017

1 reference

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Interleukin-23 drives intestinal inflammation through direct activity on T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Th memory for interleukin-17 expression is stable in vivo.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040235

Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE

28 November 2018

1 reference

12 December 2020

Human Th17 cells comprise heterogeneous subsets including IFN-gamma-producing cells with distinct properties from the Th1 lineage

1 reference

12 December 2020

GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

An interferon-gamma-producing Th1 subset is the major source of IL-17 in experimental autoimmune encephalitis

1 reference

12 December 2020

Cutting edge: an IL-17F-CreEYFP reporter mouse allows fate mapping of Th17 cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.1993

1 reference

654659

654659

1 reference

1 reference

1 reference