Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination (Q24627168)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550754%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination (English)

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8 January 2020

2

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8 January 2020

Jin Young Kim

3

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8 January 2020

Juan Sandoval

5

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8 January 2020

author name string

Jiadong Li

1

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8 January 2020

Aixiao Liu

4

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8 January 2020

Jean DeVellis

6

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8 January 2020

Patrizia Casaccia-Bonnefil

7

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8 January 2020

language of work or name

English

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publication date

1 June 2008

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8 January 2020

published in

Journal of Neuroscience

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8 January 2020

volume

28

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8 January 2020

issue

24

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8 January 2020

page(s)

6118-6127

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Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion

8 January 2020

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The complexity of p53 modulation: emerging patterns from divergent signals

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7 April 2017

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Roles for p53 and p73 during oligodendrocyte development

7 April 2017

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 April 2017

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Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

7 April 2017

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Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors.

27 September 2017

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The oncogenic roles of p53 mutants in mouse models

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Microglia and the control of autoreactive T cell responses

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Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis

27 September 2017

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Experimental autoimmune encephalomyelitis mobilizes neural progenitors from the subventricular zone to undergo oligodendrogenesis in adult mice

27 September 2017

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27 September 2017

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The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system.

27 September 2017

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A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

27 September 2017

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Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin

27 September 2017

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Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

27 September 2017

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The p53-deficient mouse: a model for basic and applied cancer studies

27 September 2017

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Regionally specific effects of BDNF on oligodendrocytes

27 September 2017

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Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination

30 May 2018

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Distinct spatial and temporal activation of caspase pathways in neurons and glial cells after excitotoxic damage to the immature rat brain.

30 May 2018

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A critical role for p53 in the control of NF-kappaB-dependent gene expression in TLR4-stimulated dendritic cells exposed to Genistein

28 November 2018

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The neurotoxic effect of cuprizone on oligodendrocytes depends on the presence of pro-inflammatory cytokines secreted by microglia.

28 November 2018

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Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors.

28 November 2018

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p53 is a suppressor of inflammatory response in mice.

28 November 2018

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Tissue preconditioning may explain concentric lesions in Baló's type of multiple sclerosis

28 November 2018

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Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination.

28 November 2018

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28 November 2018

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28 November 2018

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Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases.

28 November 2018

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A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

28 November 2018

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28 November 2018

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28 November 2018

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Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice

28 November 2018

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Growth and fate of PSA-NCAM+ precursors of the postnatal brain.

28 November 2018

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Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination

28 November 2018

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12 December 2020

Expression of Bax, Bcl-2, and P53 in progressive multifocal leukoencephalopathy

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12 December 2020

Oligodendrocyte precursor migration and differentiation: combined effects of PSA residues, growth factors, and substrates

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12 December 2020

Alterations in metabolism and gene expression in brain regions during cuprizone-induced demyelination and remyelination

1 reference

12 December 2020

Investigation of bax, bcl-2, bcl-x and p53 gene polymorphisms in multiple sclerosis

1 reference

12 December 2020

The suppression of T cell apoptosis influences the severity of disease during the chronic phase but not the recovery from the acute phase of experimental autoimmune encephalomyelitis in mice

1 reference

12 December 2020

PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination

1 reference

12 December 2020

YC-1 attenuates LPS-induced proinflammatory responses and activation of nuclear factor-kappaB in microglia.

1 reference

12 December 2020

Lack of interferon-beta leads to accelerated remyelination in a toxic model of central nervous system demyelination

1 reference

12 December 2020

Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

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12 December 2020

Gene expression in brain during cuprizone-induced demyelination and remyelination

1 reference

12 December 2020

10.1523/JNEUROSCI.0184-08.2008

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550754%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550754%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

18550754

2 references