The biology of CD44 and HCELL in hematopoiesis: the 'step 2-bypass pathway' and other emerging perspectives (Q24628178)

Current Opinion in Hematology

Europe PubMed Central

title

The biology of CD44 and HCELL in hematopoiesis: the 'step 2-bypass pathway' and other emerging perspectives (English)

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Robert Sackstein

1

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language of work or name

English

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publication date

July 2011

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published in

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volume

18

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issue

4

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page(s)

239-48

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cites work

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CD44/chondroitin sulfate proteoglycan and alpha 2 beta 1 integrin mediate human melanoma cell migration on type IV collagen and invasion of basement membranes

27 September 2017

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27 September 2017

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27 September 2017

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Glycosylation of CD44 negatively regulates its recognition of hyaluronan

27 September 2017

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Hyaluronan binding by CD44 is regulated by a phosphorylation-independent mechanism.

27 September 2017

1 reference

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ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

27 September 2017

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Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man.

27 September 2017

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Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits

27 September 2017

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Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures

27 September 2017

1 reference

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Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition

27 September 2017

1 reference

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Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons

27 September 2017

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Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis

27 September 2017

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Post-translational protein modification and expression of ankyrin-binding site(s) in GP85 (Pgp-1/CD44) and its biosynthetic precursors during T-lymphoma membrane biosynthesis

27 September 2017

1 reference

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A cell surface chondroitin sulfate proteoglycan, immunologically related to CD44, is involved in type I collagen-mediated melanoma cell motility and invasion

27 September 2017

1 reference

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The Core Protein of Epican, a Heparan Sulfate Proteoglycan on Keratinocytes, Is an Alternative Form of CD44

27 September 2017

1 reference

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Keratan sulfate modification of CD44 modulates adhesion to hyaluronate

27 September 2017

1 reference

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CD44: structure, function, and association with the malignant process.

27 September 2017

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Epican, a heparan/chondroitin sulfate proteoglycan form of CD44, mediates cell-cell adhesion.

27 September 2017

1 reference

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The HGF/c-Met axis synergizes with G-CSF in the mobilization of hematopoietic stem/progenitor cells

27 September 2017

1 reference

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Growth and differentiation regulate CD44 expression on human keratinocytes

30 May 2018

1 reference

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CD44 variant exon v5 encodes a tyrosine that is sulphated.

30 May 2018

1 reference

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The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor. Comparison of all 10 variable exons between mouse, human, and rat.

30 May 2018

1 reference

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Differentiation-associated changes in CD44 isoform expression during normal hematopoiesis and their alteration in chronic myeloid leukemia.

30 May 2018

1 reference

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Proteoglycans in human long-term bone marrow cultures: biochemical and ultrastructural analyses.

30 May 2018

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Acylation of the lymphoma transmembrane glycoprotein, GP85, may be required for GP85-ankyrin interaction

30 May 2018

1 reference

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A CD44-like endothelial cell transmembrane glycoprotein (GP116) interacts with extracellular matrix and ankyrin

30 May 2018

1 reference

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Studies of the haemopoietic microenvironment. II. Content of glycosaminoglycans in murine bone marrow and spleen under anaemic and polycythaemic conditions

30 May 2018

1 reference

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Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling

30 May 2018

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MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization

28 November 2018

1 reference

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G-CSF induces E-selectin ligand expression on human myeloid cells.

28 November 2018

1 reference

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Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4-/- chimeric mice.

28 November 2018

1 reference

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RANTES (CCL5) induces a CCR5-dependent accelerated shedding of syndecan-1 (CD138) and syndecan-4 from HeLa cells and forms complexes with the shed ectodomains of these proteoglycans as well as with those of CD44.

28 November 2018

1 reference

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Hyaluronic acid facilitates the recovery of hematopoiesis following 5-fluorouracil administration

28 November 2018

1 reference

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CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow.

28 November 2018

1 reference

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Fibroblast invasive migration into fibronectin/fibrin gels requires a previously uncharacterized dermatan sulfate-CD44 proteoglycan

28 November 2018

1 reference

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Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.

28 November 2018

1 reference

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Tumor necrosis factor-alpha induces functionally active hyaluronan-adhesive CD44 by activating sialidase through p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated human monocytic cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145154

Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145154

CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145154

Synergistic effects of hepatocyte growth factor on human cord blood CD34+ progenitor cells are the result of c-met receptor expression

28 November 2018

1 reference

12 December 2020

Requirement for CD44 in proliferation and homing of hematopoietic precursor cells

1 reference

12 December 2020

Expression of CD44 variant isoforms in peripheral blood leukocytes in malignant lymphoma and leukemia: inverse correlation between expression and tumor progression

1 reference

12 December 2020

Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia

1 reference

12 December 2020

CD44-ligation induces, through ERK1/2 pathway, synthesis of cytokines TNF-alpha and IL-6 required for differentiation of THP-1 monoblastic leukemia cells

1 reference

12 December 2020

Hyaluronan-dependent cell migration can be blocked by a CD44 cytoplasmic domain peptide containing a phosphoserine at position 325

1 reference

12 December 2020

TNF-alpha induction of CD44-mediated leukocyte adhesion by sulfation

1 reference

12 December 2020

CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis

1 reference

12 December 2020

Characterization of the heparan sulfate and chondroitin sulfate assembly sites in CD44

1 reference

12 December 2020

TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44

1 reference

12 December 2020

Expression of the c-ErbB-2/HER2 proto-oncogene in normal hematopoietic cells

1 reference

12 December 2020

CD34+Cells and CD34+CD38–Subset from Mobilized Blood Show Different Patterns of Adhesion Molecules Compared to Those from Steady-State Blood, Bone Marrow, and Cord Blood

1 reference

12 December 2020

Studies of the hemopoietic microenvironments. V. Changes in murine splenic and bone marrow glycosaminoglycans during post irradiation hemopoietic regeneration

1 reference

12 December 2020

Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells

1 reference

12 December 2020

Hematopoietic progenitor cell expression of the H-CAM (CD44) homing-associated adhesion molecule

1 reference

12 December 2020

Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

1 reference

12 December 2020

Participation in normal immune responses of a metastasis-inducing splice variant of CD44

1 reference

12 December 2020

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

1 reference

12 December 2020

A PCR-based method for the analysis of human CD44 splice products

1 reference

12 December 2020

Adhesion of committed human hematopoietic progenitors to synthetic peptides from the C-terminal heparin-binding domain of fibronectin: cooperation between the integrin alpha 4 beta 1 and the CD44 adhesion receptor

1 reference

12 December 2020

Involvement of CD44 variant isoforms in hyaluronate adhesion by human activated T cells

1 reference

12 December 2020

Heparan sulfate proteoglycan isoforms of the CD44 hyaluronan receptor induced in human inflammatory macrophages can function as paracrine regulators of fibroblast growth factor action

1 reference

12 December 2020

Mobilization kinetics of CD34(+) cells in association with modulation of CD44 and CD31 expression during continuous intravenous administration of G-CSF in normal donors

1 reference

12 December 2020

Combining G-CSF with a blockade of adhesion strongly improves the reconstitutive capacity of mobilized hematopoietic progenitor cells

1 reference

12 December 2020

CD44 variant-specific antibodies trigger hemopoiesis by selective release of cytokines from bone marrow macrophages

1 reference

12 December 2020

Role of hepatocyte growth factor in hemopoiesis

1 reference

12 December 2020

CD44-mediated adhesiveness of human hematopoietic progenitors to hyaluronan is modulated by cytokines

1 reference

12 December 2020

Expression of CD44 isoforms by highly enriched CD34-positive cells in cord blood, bone marrow and leukaphereses

1 reference

12 December 2020