Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail (Q24628981)

2

S

Eschenburg

1 reference

19 October 2023

W A Shuttleworth

3

W A

Shuttleworth

1 reference

19 October 2023

J V Schloss

4

J V

Schloss

1 reference

19 October 2023

N Amrhein

5

N

Amrhein

1 reference

19 October 2023

J N Evans

6

J N

Evans

1 reference

19 October 2023

W Kabsch

7

W

Proceedings of the National Academy of Sciences of the United States of America

Kabsch

1 reference

19 October 2023

language of work or name

English

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publication date

13 February 2001

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published in

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volume

98

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issue

4

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page(s)

1376-80

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cites work

Structure and topological symmetry of the glyphosate target 5-enolpyruvylshikimate-3-phosphate synthase: a distinctive protein fold

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Comparative X-ray analysis of the un-liganded fosfomycin-target murA

7 April 2017

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Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA

7 April 2017

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Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA

7 April 2017

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Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin

7 April 2017

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Atomic structure of the actin:DNase I complex

7 April 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

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Improved methods for building protein models in electron density maps and the location of errors in these models

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The H385N mutant of 5-enolpyruvylshikimate-3-phosphate synthase: kinetics, fluorescence, and nuclear magnetic resonance studies

7 April 2017

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The versatility of phosphoenolpyruvate and its vinyl ether products in biosynthesis

27 September 2017

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Site-directed mutagenesis and NMR studies of histidine-385 mutants of 5-enolpyruvylshikimate-3-phosphate synthase

27 September 2017

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The herbicide glyphosate is a potent inhibitor of 5-enolpyruvyl-shikimic acid-3-phosphate synthase

27 September 2017

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The mechanism of action of fosfomycin (phosphonomycin)

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Amino acid biosynthesis inhibitors as herbicides

27 September 2017

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The shikimate pathway--a metabolic tree with many branches

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Evidence for the shikimate pathway in apicomplexan parasites.

27 September 2017

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Studies on the conformational changes in the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyltransferase (MurA).

30 May 2018

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On the mechanism of 5-enolpyruvylshikimate 3-phosphate synthetase.

30 May 2018

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Over-production of 5-enolpyruvylshikimate-3-phosphate synthase in Escherichia coli: use of the T7 promoter

30 May 2018

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Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

30 May 2018

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Structural constraints on the ternary complex of 5-enolpyruvylshikimate-3-phosphate synthase from rotational-echo double-resonance NMR.

21 January 2018

1 reference

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Substitution of Gly-96 to Ala in the 5-enolpyruvylshikimate-3-phosphate synthase of Klebsiella pneumoniae results in a greatly reduced affinity for the herbicide glyphosate.

21 January 2018

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Analysis of Fluoromethyl Group Chirality Establishes a Common Stereochemical Course for the Enolpyruvyl Transfers Catalyzed by EPSP Synthase and UDP-GlcNAc Enolpyruvyl Transferase†

21 January 2018

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Ligand geometry of the ternary complex of 5-enolpyruvylshikimate-3-phosphate synthase from rotational-echo double-resonance NMR

21 January 2018

1 reference

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THE ENZYMATIC FORMATION AND ISOLATION OF 3-ENOLPYRUVYLSHIKIMATE 5-PHOSPHATE

28 November 2018

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12 December 2020

5-Enolpyruvylshikimate-3-phosphate synthase of Klebsiella pneumoniae 2. Inhibition by glyphosate [N-(phosphonomethyl)glycine]

1 reference

12 December 2020

Site-directed mutagenesis of putative active site residues of 5-enolpyruvylshikimate-3-phosphate synthase

1 reference

12 December 2020

Kinetics of 5-enolpyruvylshikimate-3-phosphate synthase inhibition by glyphosate

1 reference

12 December 2020

5-Enolpyruvylshikimate-3-phosphate synthase of Bacillus subtilis is an allosteric enzyme. Analysis of Arg24-->Asp, Pro105-->Ser and His385-->Lys mutations suggests a hidden phosphoenolpyruvate-binding site

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.98.4.1376

1 reference

598784

ADS bibcode

2001PNAS...98.1376S

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598784

1 reference

1 reference

1 reference