AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency (Q24629585)

GOA release 2020-03-11

Gerald I Shulman

9

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Varman T Samuel

8

Varman T Samuel

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Krista A Varady

5

Krista A Varady

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Marc Hellerstein

6

Marc K Hellerstein

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Hei Sook Sul

13

Hei Sook Sul

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Maryam Ahmadian

2

Maryam Ahmadian

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Chulho Kang

12

Chulho Kang

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author name string

Kathy Jaworski

1

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Robin E Duncan

3

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Eszter Sarkadi-Nagy

4

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Hui-Young Lee

7

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Kee-Hong Kim

10

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Sarah de Val

Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA)

11

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language of work or name

English

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publication date

February 2009

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published in

Nature Medicine

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volume

15

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page(s)

159-68

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issue

2

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cites work

1 reference

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A simple method for the isolation and purification of total lipides from animal tissues

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Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

7 April 2017

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Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation

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Regulation of lipolysis in adipocytes

27 September 2017

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The phospholipase A2 superfamily and its group numbering system

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Partnering between monomers of cyclooxygenase-2 homodimers

27 September 2017

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Distinguishing phospholipase A2 types in biological samples by employing group-specific assays in the presence of inhibitors

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A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation

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Expression and identification of p90 as the murine mitochondrial glycerol-3-phosphate acyltransferase

27 September 2017

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Release and effects of prostaglandins in adipose tissue.

27 September 2017

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Biphasic effects of prostaglandin E2 on the human fat cell adenylate cyclase

27 September 2017

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Optimized conditions for measuring lipolysis in murine primary adipocytes

27 September 2017

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Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases

30 May 2018

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Role of cyclooxygenases COX-1 and COX-2 in modulating adipogenesis in 3T3-L1 cells

30 May 2018

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Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?

30 May 2018

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Eicosanoids as endogenous regulators of leptin release and lipolysis by mouse adipose tissue in primary culture

30 May 2018

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Prostacyclin IP receptor up-regulates the early expression of C/EBPbeta and C/EBPdelta in preadipose cells

30 May 2018

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The lack of bimodality in the effects of endogenous and exogenous prostaglandins on fat cell lipolysis in rats

30 May 2018

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Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma

30 May 2018

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30 May 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice

28 November 2018

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Understanding adipocyte differentiation

28 November 2018

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Fasting does not impair insulin-stimulated glucose uptake but alters intracellular glucose metabolism in conscious rats.

28 November 2018

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Expression of human hormone-sensitive lipase in white adipose tissue of transgenic mice increases lipase activity but does not enhance in vitro lipolysis

28 November 2018

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12 December 2020

Prostacyclin is a specific effector of adipose cell differentiation. Its dual role as a cAMP- and Ca(2+)-elevating agent

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12 December 2020

Prostaglandin E2 can bimodally inhibit and stimulate the epididymal adipocyte adenylyl cyclase activity

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12 December 2020

Protein kinase C deficiency increases fatty acid oxidation and reduces fat storage

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12 December 2020

Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha

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12 December 2020

Eliminating the antilipolytic adenosine A1 receptor does not lead to compensatory changes in the antilipolytic actions of PGE2 and nicotinic acid

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12 December 2020