Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis (Q24629969)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139991%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis (English)

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17 January 2020

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17 January 2020

Xiaowei Sherry Liu

4

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17 January 2020

Anil Kumar Balapure

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17 January 2020

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Michael D Gershon

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17 January 2020

author name string

Santhanam Balaji

2

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17 January 2020

Padmanaban S Suresh

3

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17 January 2020

Xin Lu

5

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17 January 2020

Zhishan Li

6

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17 January 2020

X Edward Guo

7

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17 January 2020

J John Mann

8

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17 January 2020

Rudraiah Medhamurthy

11

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17 January 2020

Marc Vidal

12

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17 January 2020

Gerard Karsenty

13

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17 January 2020

Patricia Ducy

14

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17 January 2020

language of work or name

English

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publication date

7 February 2010

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17 January 2020

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17 January 2020

volume

16

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17 January 2020

issue

3

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17 January 2020

page(s)

308-312

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Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum

17 January 2020

cites work

1 reference

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Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin

7 April 2017

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Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

7 April 2017

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Relationship between central and peripheral serotonin indexes in depressed and suicidal psychiatric inpatients

7 April 2017

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Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters

7 April 2017

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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

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Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

7 April 2017

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A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure

7 April 2017

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Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders

27 September 2017

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Discovery and characterization of novel tryptophan hydroxylase inhibitors that selectively inhibit serotonin synthesis in the gastrointestinal tract

27 September 2017

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The serotonin signaling system: from basic understanding to drug development for functional GI disorders

27 September 2017

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Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice

27 September 2017

1 reference

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Parathyroid hormone and teriparatide for the treatment of osteoporosis: a review of the evidence and suggested guidelines for its use.

27 September 2017

1 reference

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Pharmacological treatment of osteopenia induced by gastrectomy or ovariectomy in young female rats

27 September 2017

1 reference

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Leptin regulates bone formation via the sympathetic nervous system

27 September 2017

1 reference

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Therapeutic approaches to bone diseases

27 September 2017

1 reference

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Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus.

27 September 2017

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Basic biomechanical measurements of bone: a tutorial

27 September 2017

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Effects of parathyroid hormone and alendronate alone or in combination in osteoporosis

27 September 2017

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The direct examination of three-dimensional bone architecture in vitro by computed tomography

28 November 2018

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12 December 2020

Sex steroids and bone

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12 December 2020

Anabolic and catabolic bone effects of human parathyroid hormone (1-34) are predicted by duration of hormone exposure

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12 December 2020

The Conneulor: unbiased estimation of connectivity using physical disectors under projection

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Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop

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Identifiers

DOI

10.1038/NM.2098

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139991%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 January 2020

1017779006

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139991%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20139991%20AND%20SRC:MED&resulttype=core&format=json