Structural and functional characterization of a novel homodimeric three-finger neurotoxin from the venom of Ophiophagus hannah (king cobra) (Q24633112)

2

0 references

Ming Zhi Chong

3

0 references

Dieter D'hoedt

4

0 references

Chun Shin Foo

5

0 references

Nandhakishore Rajagopalan

6

0 references

Selvanayagam Nirthanan

7

0 references

Daniel Bertrand

8

0 references

J Sivaraman

9

0 references

R Manjunatha Kini

Journal of Biological Chemistry

10

0 references

language of work or name

English

0 references

publication date

12 March 2010

0 references

published in

0 references

volume

285

0 references

issue

11

0 references

page(s)

8302-15

0 references

cites work

Coevolution of diet and prey-specific venom activity supports the role of selection in snake venom evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Expression pattern of three-finger toxin and phospholipase A2 genes in the venom glands of two sea snakes, Lapemis curtus and Acalyptophis peronii: comparison of evolution of these toxins in land snakes, sea kraits and sea snakes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

7 April 2017

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Calciseptine, a peptide isolated from black mamba venom, is a specific blocker of the L-type calcium channel

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

NMR structure of bucandin, a neurotoxin from the venom of the Malayan krait (Bungarus candidus)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Crystal structure of kappa-bungarotoxin at 2.3-A resolution

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Inference of macromolecular assemblies from crystalline state

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Coot: model-building tools for molecular graphics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Automated protein model building combined with iterative structure refinement

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

ESPript: analysis of multiple sequence alignments in PostScript

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Therapeutic potential of venom peptides

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Use of a snake venom toxin to characterize the cholinergic receptor protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Muscarinic toxins: tools for the study of the pharmacological and functional properties of muscarinic receptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

New weak toxins from the cobra venom

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Naturally occurring disulfide-bound dimers of three-fingered toxins: a paradigm for biological activity diversification

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

The venom gland transcriptome of the Desert Massasauga rattlesnake (Sistrurus catenatus edwardsii): towards an understanding of venom composition among advanced snakes (Superfamily Colubroidea).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Beta-cardiotoxin: a new three-finger toxin from Ophiophagus hannah (king cobra) venom with beta-blocker activity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Isolation and pharmacological characterisation of hostoxin-1, a postsynaptic neurotoxin from the venom of the Stephen's banded snake (Hoplocephalus stephensi).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Isolation and pharmacological characterisation of papuantoxin-1, a postsynaptic neurotoxin from the venom of the Papuan black snake (Pseudechis papuanus).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Ohanin, a novel protein from king cobra venom, induces hypolocomotion and hyperalgesia in mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Three-finger alpha-neurotoxins and the nicotinic acetylcholine receptor, forty years on.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Neuromuscular effects of candoxin, a novel toxin from the venom of the Malayan krait (Bungarus candidus).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Molecular moulds with multiple missions: functional sites in three-finger toxins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Candoxin, a novel toxin from Bungarus candidus, is a reversible antagonist of muscle (alphabetagammadelta ) but a poorly reversible antagonist of neuronal alpha 7 nicotinic acetylcholine receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

STRAP: editor for STRuctural Alignments of Proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Snake venom alpha-neurotoxins and other 'three-finger' proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Snake venom cardiotoxins-structure, dynamics, function and folding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Observations on the isolated phrenic nerve diaphragm preparation of the rat. 1946.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Diet and snake venom evolution

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Genetic engineering of snake toxins. The functional site of Erabutoxin a, as delineated by site-directed mutagenesis, includes variant residues

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Severe neurotoxic envenoming by the Malayan krait Bungarus candidus (Linnaeus): response to antivenom and anticholinesterase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

The TiPS lecture. The nicotinic acetylcholine receptor: an allosteric protein prototype of ligand-gated ion channels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Pharmacology of neuronal nicotinic acetylcholine receptor subtypes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

The isolated chick biventer cervicis nerve-muscle preparation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Selectivity profile of muscarinic toxin 3 in functional assays of cloned and native receptors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Molecular evolution of snake toxins: is the functional diversity of snake toxins associated with a mechanism of accelerated evolution?

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

κ-Bungarotoxin: binding of a neuronal nicotinic receptor antagonist to chick optic lobe and skeletal muscle

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Distance between the agonist and noncompetitive inhibitor sites on the nicotinic acetylcholine receptor.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Kappa-neurotoxins: heterodimer formation between different neuronal nicotinic receptor antagonists

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Mambin, a potent glycoprotein IIb-IIIa antagonist and platelet aggregation inhibitor structurally related to the short neurotoxins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832981

Toxins 'R' Us: more pharmacological tools from nature's superstore

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Effects of muscarinic toxins MT1 and MT2 from green mamba on different muscarinic cholinoceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Pharmacological characterisation of a neurotoxin from the venom of Boiga dendrophila (mangrove catsnake).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

An automated system for intracellular and intranuclear injection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Insulin regulates neuronal M2 muscarinic receptor function in the ileum of diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Decreased parasympathetic activities in Malayan krait (Bungarus candidus) envenoming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

MOLREP: an Automated Program for Molecular Replacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Venom of the Brown Treesnake, Boiga irregularis: ontogenetic shifts and taxa-specific toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

How do short neurotoxins bind to a muscular-type nicotinic acetylcholine receptor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Differential roles for disulfide bonds in the structural integrity and biological activity of kappa-Bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Site-directed mutagenesis of kappa-bungarotoxin: implications for neuronal receptor specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

Critical interactions at the dimer interface of kappa-bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.074161

How do snake curaremimetic toxins discriminate between nicotinic acetylcholine receptor subtypes

21 January 2018

1 reference

12 December 2020

Primary structure of γ-bungarotoxin, a new postsynaptic neurotoxin from venom of Bungarus multicinctus

1 reference

12 December 2020

Variability among the sites by which curaremimetic toxins bind to torpedo acetylcholine receptor, as revealed by identification of the functional residues of alpha-cobratoxin

1 reference

12 December 2020

Do structural deviations between toxins adopting the same fold reflect functional differences?

1 reference

12 December 2020

Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor

1 reference

12 December 2020

Nicotinic receptors in wonderland

1 reference

12 December 2020

A study of the desensitization produced by acetylcholine at the motor end-plate

1 reference

12 December 2020

On the contraction of muscle, chiefly in relation to the presence of "receptive" substances: Part I

1 reference

12 December 2020

Solution structure of neuronal bungarotoxin determined by two-dimensional NMR spectroscopy: sequence-specific assignments, secondary structure, and dimer formation.

1 reference

12 December 2020

Isolation and pharmacological characterization of a new alpha-neurotoxin (alpha-AgTx) from venom of the viper Agkistrodon halys (Pallas)

1 reference

12 December 2020

kappa-Bungarotoxin: complete amino acid sequence of a neuronal nicotinic receptor probe

1 reference

12 December 2020

kappa-Bungarotoxin. Self-association of a neuronal nicotinic receptor probe

1 reference

12 December 2020

N-hydroxysulfosuccinimide active esters: bis(N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers

1 reference

12 December 2020

Refolding of reduced short neurotoxins: circular dichroism analysis

1 reference

12 December 2020

Nicotinic acetylcholine receptor at 9 A resolution.

1 reference

12 December 2020

Characterization of postjunctional muscarinic receptors mediating contraction in rat anococcygeus muscle

1 reference

12 December 2020