Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea (Q24633203)

Vaccines for gonorrhea: can we rise to the challenge?

Europe PubMed Central

title

Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea (English)

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main subject

gonorrhea

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multiple drug resistance

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1

Magnus Unemo

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author name string

Robert A Nicholas

series ordinal

2

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language of work or name

English

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publication date

December 2012

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published in

Future Microbiology

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volume

7

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page(s)

1401-22

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issue

12

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cites work

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Antibiotic-resistant phenotypes and genotypes of Neisseria gonorrhoeae isolates in Japan: identification of strain clusters with multidrug-resistant phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Treatment of uncomplicated gonococcal urethritis by double-dosing of 200 mg cefixime at a 6-h interval

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain.

21 January 2018

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Antimicrobial resistance in clinical isolates of Neisseria subflava from the oral cavities of a Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Comparison of Neisseria gonorrhoeae isolates from the genital tract and pharynx of two gonorrhea patients

21 January 2018

1 reference

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Analysis of mutations within multiple genes associated with resistance in a clinical isolate of Neisseria gonorrhoeae with reduced ceftriaxone susceptibility that shows a multidrug-resistant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Using strain typing to characterise a fluoroquinolone-resistant Neisseria gonorrhoeae transmission network in southern California

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Emergence of cephem- and aztreonam-high-resistant Neisseria gonorrhoeae that does not produce beta-lactamase

21 January 2018

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https://api.crossref.org/works/10.2217%2FFMB.12.117

Successful treatment with faropenem and clarithromycin of pulmonary Mycobacterium abscessus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Emergence and characterization of Neisseria gonorrhoeae isolates with decreased susceptibilities to ceftriaxone and cefixime in Canada: 2001-2010.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Retrospective analysis of antimicrobial susceptibility trends (2000-2009) in Neisseria gonorrhoeae isolates from countries in Latin America and the Caribbean shows evolving resistance to ciprofloxacin, azithromycin and decreased susceptibility to ce

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Analysis of mutations in multiple loci of Neisseria gonorrhoeae isolates reveals effects of PIB, PBP2 and MtrR on reduced susceptibility to ceftriaxone

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Sustainable antimicrobial surveillance programs essential for controlling Neisseria gonorrhoeae superbug

21 January 2018

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https://api.crossref.org/works/10.2217%2FFMB.12.117

Ceftriaxone-resistant Neisseria gonorrhoeae, Japan

21 January 2018

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https://api.crossref.org/works/10.2217%2FFMB.12.117

Using the Neisseria gonorrhoeae multiantigen sequence-typing method to assess strain diversity and antibiotic resistance in San Francisco, California

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Analysis of amino acid sequences of penicillin-binding protein 2 in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime and ceftriaxone

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is associated with mutations G542S, P551S and P551L in the gonococcal penicillin-binding protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Reduced susceptibility to ceftriaxone in Neisseria gonorrhoeae is spread internationally by genetically distinct gonococcal populations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Towards an understanding of chromosomally mediated penicillin resistance in Neisseria gonorrhoeae: evidence for a porin-efflux pump collaboration

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Mutations causing in vitro resistance to azithromycin in Neisseria gonorrhoeae

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Implications of current recommendations for third-generation cephalosporin use in the WHO Western Pacific Region following the emergence of multiresistant gonococci

21 January 2018

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https://api.crossref.org/works/10.2217%2FFMB.12.117

Single dose 1 g ceftriaxone for urogenital and pharyngeal infection caused by Neisseria gonorrhoeae

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Pharyngeal gonorrhoea - is dual therapy the way forward?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

GAR-936 (9-t-butylglycylamido-minocycline) susceptibility test development for streptococci, Haemophilus influenzae and Neisseria gonorrhoeae: preliminary guidelines and interpretive criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Should tigecycline be considered for urinary tract infections? A pharmacokinetic re-evaluation

21 January 2018

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https://api.crossref.org/works/10.2217%2FFMB.12.117

Protocol for the molecular detection of antibiotic resistance mechanisms in Neisseria gonorrhoeae.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Real-time PCR and subsequent pyrosequencing for screening of penA mosaic alleles and prediction of reduced susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.117

Enhanced gonococcal antimicrobial surveillance in the era of ceftriaxone resistance: a real-time PCR assay for direct detection of the Neisseria gonorrhoeae H041 strain

21 January 2018

1 reference

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Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific and South East Asian Regions, 2010.

21 January 2018

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Antimicrobial susceptibility and penicillin-binding protein 1 and 2 mutations in Neisseria gonorrhoeae isolated from male urethritis in Sapporo, Japan

28 November 2018

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Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011.

28 November 2018

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The European gonococcal antimicrobial surveillance programme, 2009.

28 November 2018

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Cephalosporin susceptibility among Neisseria gonorrhoeae isolates--United States, 2000-2010.

28 November 2018

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Ceftriaxone treatment failure of pharyngeal gonorrhoea verified by international recommendations, Sweden, July 2010.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629839

The Russian gonococcal antimicrobial susceptibility programme (RU-GASP)--national resistance prevalence in 2007 and 2008, and trends during 2005-2008.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629839

Threat to cefixime treatment for gonorrhea

28 November 2018

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A remarkable reduction in the susceptibility of Neisseria gonorrhoeae isolates to cephems and the selection of antibiotic regimens for the single-dose treatment of gonococcal infection in Japan

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3629839

Global transmission of multiple-drug resistant Neisseria gonorrhoeae strains refractive to cephalosporin treatment

28 November 2018

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Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010

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12 December 2020

The serious threat of multidrug-resistant and untreatable gonorrhoea: the pressing need for global action to control the spread of antimicrobial resistance, and mitigate the impact on sexual and reproductive health

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12 December 2020

In vitro synergistic effects of double combinations of beta-lactams and azithromycin against clinical isolates of Neisseria gonorrhoeae

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12 December 2020

2009 European (IUSTI/WHO) guideline on the diagnosis and treatment of gonorrhoea in adults

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12 December 2020

Cephalosporin resistantNeisseria gonorrhoeae: time to consider gentamicin?

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12 December 2020

Use of a novel screening PCR indicates presence of Neisseria gonorrhoeae isolates with a mosaic penA gene sequence in Australia

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12 December 2020

Surveillance of antimicrobial susceptibilities in Neisseria gonorrhoeae in Nanjing, China, 1999-2006

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12 December 2020

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12 December 2020

[Nationwide antimicrobial susceptibility survey of Neisseria gonorrhoeae isolates in Japan]

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12 December 2020

Regulation of the MtrC-MtrD-MtrE efflux-pump system modulates the in vivo fitness of Neisseria gonorrhoeae

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12 December 2020

Gonorrhoea surveillance, laboratory diagnosis and antimicrobial susceptibility testing of Neisseria gonorrhoeae in 11 countries of the eastern part of the WHO European region

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12 December 2020

Novel meningococcal 4CMenB vaccine antigens - prevalence and polymorphisms of the encoding genes in Neisseria gonorrhoeae

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12 December 2020

Neisseria gonorrhoeae with high-level resistance to azithromycin: case report of the first isolate identified in the United States

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12 December 2020

Reduction of concentration of HIV-1 in semen after treatment of urethritis: implications for prevention of sexual transmission of HIV-1. AIDSCAP Malawi Research Group

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Fluoroquinolone resistance in Neisseria gonorrhoeae: fitness cost or benefit?

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12 December 2020

First Neisseria gonorrhoeae strain with resistance to cefixime causing gonorrhoea treatment failure in Austria, 2011

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12 December 2020

Reduction of concentration of HIV-1 in semen after treatment of urethritis: implications for prevention of sexual transmission of HIV-1

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7 January 2021