Alphavirus replicon-based enhancement of mucosal and systemic immunity is linked to the innate response generated by primary immunization (Q24634730)

2

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Tracie Todd

3

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Clayton W Beard

4

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Robert E Johnston

5

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Mario Barro

Alphavirus-adjuvanted norovirus-like particle vaccines: heterologous, humoral, and mucosal immune responses protect against murine norovirus challenge

6

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language of work or name

English

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publication date

19 April 2010

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published in

Vaccine

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volume

28

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issue

18

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page(s)

3238-46

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cites work

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Replicon particles of Venezuelan equine encephalitis virus as a reductionist murine model for encephalitis

7 April 2017

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Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen.

27 September 2017

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Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node

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How do adjuvants work? Important considerations for new generation adjuvants

27 September 2017

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Development and preclinical evaluation of an alphavirus replicon vaccine for influenza

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Development and preclinical evaluation of an alphavirus replicon particle vaccine for cytomegalovirus

27 September 2017

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Alphaviral vector-transduced dendritic cells are successful therapeutic vaccines against neu-overexpressing tumors in wild-type mice

27 September 2017

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Multivalent norovirus vaccines induce strong mucosal and systemic blocking antibodies against multiple strains

27 September 2017

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CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

27 September 2017

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Mucosal and systemic adjuvant activity of alphavirus replicon particles.

27 September 2017

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Mucosal vaccines: the promise and the challenge

27 September 2017

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Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis

27 September 2017

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Generation of improved mucosal vaccines by induction of innate immunity.

27 September 2017

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A novel viral system for generating antigen-specific T cells

27 September 2017

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G-CSF: a key regulator of neutrophil production, but that's not all!

27 September 2017

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The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation

27 September 2017

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HIV-1 vaccination administered intramuscularly can induce both systemic and mucosal T cell immunity in HIV-1-uninfected individuals

27 September 2017

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Systemic, mucosal, and heterotypic immune induction in mice inoculated with Venezuelan equine encephalitis replicons expressing Norwalk virus-like particles

27 September 2017

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IFN-gamma production by antigen-presenting cells: mechanisms emerge.

27 September 2017

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Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles

27 September 2017

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CD69 and regulation of the immune function

27 September 2017

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Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo

27 September 2017

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Mucosal immunity induced by parenteral immunization with a live attenuated Venezuelan equine encephalitis virus vaccine candidate

27 September 2017

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27 September 2017

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27 September 2017

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Type I interferon-mediated stimulation of T cells by CpG DNA

27 September 2017

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30 May 2018

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30 May 2018

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Attenuating mutations in the E2 glycoprotein gene of Venezuelan equine encephalitis virus: construction of single and multiple mutants in a full-length cDNA clone

30 May 2018

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In vivo adjuvant activity of the RNA component of the Sm/RNP lupus autoantigen

30 May 2018

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The induction of HIV Gag-specific CD8+ T cells in the spleen and gut-associated lymphoid tissue by parenteral or mucosal immunization with recombinant Listeria monocytogenes HIV Gag.

28 November 2018

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An immunological profile of Balb/c mice protected from airborne challenge following vaccination with a live attenuated Venezuelan equine encephalitis virus vaccine

28 November 2018

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Induction of Virus-Specific Antibody Production by Lamina Propria Lymphocytes following Intramuscular Inoculation with Rotavirus

28 November 2018

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Parenteral and mucosal prime-boost immunization strategies in mice with hepatitis B surface antigen and CpG DNA

28 November 2018

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A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques

7 January 2021

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The induction of systemic and mucosal immune responses following the subcutaneous immunization of mature adult mice: characterization of the antibodies in mucosal secretions of animals immunized with antigen formulations containing a vitamin D3 adju

7 January 2021

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Anti-capsular polysaccharide antibody concentrations in saliva after immunization with Haemophilus influenzas type b conjugate vaccines

7 January 2021

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Removal of endotoxin from protein solutions by phase separation using Triton X-114

7 January 2021

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The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells

7 January 2021

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Murine plasmacytoid dendritic cells produce IFN-gamma upon IL-4 stimulation

7 January 2021

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Induction of interferon-gamma from natural killer cells by immunostimulatory CpG DNA is mediated through plasmacytoid-dendritic-cell-produced interferon-alpha and tumour necrosis factor-alpha

7 January 2021

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7 January 2021

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Heterogeneity among resident murine peritoneal macrophages: separation and functional characterization of monocytoid cells producing granulocyte-macrophage colony-stimulating factor (GM-CSF) and responding to regulation by lactoferrin

7 January 2021

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20184975

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IL-1 is an effective adjuvant for mucosal and systemic immune responses when coadministered with protein immunogens

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20184975