Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein (Q24635842)

Michael P Washburn

Małgorzata Kęsik-Brodacka

8

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5

Malgorzata Kesik-Brodacka

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Selene K Swanson

4

Selene K Swanson

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Kasia Hrecka

1

Kasia Hrecka

0 references

Caili Hao

2

Caili Hao

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Smita Srivastava

6

Smita Srivastava

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author name string

Magda Gierszewska

3

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Jacek Skowronski

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

9

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language of work or name

English

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publication date

30 June 2011

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published in

Nature

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volume

474

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page(s)

658-61

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issue

7353

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cites work

1 reference

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Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

7 April 2017

1 reference

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The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection

7 April 2017

1 reference

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Trex1 prevents cell-intrinsic initiation of autoimmunity

7 April 2017

1 reference

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Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

7 April 2017

1 reference

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HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

7 April 2017

1 reference

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Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

7 April 2017

1 reference

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Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection

7 April 2017

1 reference

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The challenge of viral reservoirs in HIV-1 infection

7 April 2017

1 reference

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In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

7 April 2017

1 reference

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The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

7 April 2017

1 reference

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HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179858

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

27 September 2017

1 reference

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Cellular restriction targeting viral capsids perturbs human immunodeficiency virus type 1 infection of nondividing cells

27 September 2017

1 reference

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A cellular restriction dictates the permissivity of nondividing monocytes/macrophages to lentivirus and gammaretrovirus infection

27 September 2017

1 reference

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Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

27 September 2017

1 reference

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Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells

27 September 2017

1 reference

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SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells

27 September 2017

1 reference

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Dendritic cells: translating innate to adaptive immunity.

27 September 2017

1 reference

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A quantitative assay for HIV DNA integration in vivo

27 September 2017

1 reference

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Characterization of novel safe lentiviral vectors derived from simian immunodeficiency virus (SIVmac251) that efficiently transduce mature human dendritic cells

27 September 2017

1 reference

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Vpx is required for dissemination and pathogenesis of SIV(SM) PBj: evidence of macrophage-dependent viral amplification.

27 September 2017

1 reference

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Progression to AIDS in the absence of a gene for vpr or vpx.

27 September 2017

1 reference

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VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179858

The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179858

Vpx association with mature core structures of HIV-2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179858

HIV-2 viral protein X association with the GAG p27 capsid protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179858

Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179858

Refinements to label free proteome quantitation: how to deal with peptides shared by multiple proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179858

Proteomic Analysis by Multidimensional Protein Identification Technology

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21720370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10195

1 reference

Dimensions Publication ID

637050

1037288305

0 references

637050

1 reference

1 reference

1 reference