Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity (Q24642507)

Current Opinion in Pharmacology

Europe PubMed Central

title

Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity (English)

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4

Richard A Flavell

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author name string

Shomyseh Sanjabi

series ordinal

1

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Lauren A Zenewicz

series ordinal

2

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Masahito Kamanaka

series ordinal

3

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language of work or name

English

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publication date

August 2009

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published in

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Interleukin-10: new perspectives on an old cytokine

volume

9

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issue

4

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page(s)

447-53

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cites work

1 reference

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Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

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Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice

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TGF-beta: a master of all T cell trades

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Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

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RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells

27 September 2017

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IL-22 and inflammation: leukin' through a glass onion

27 September 2017

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Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells

27 September 2017

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Transforming growth factor-beta suppresses the activation of CD8+ T-cells when naive but promotes their survival and function once antigen experienced: a two-faced impact on autoimmunity

27 September 2017

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TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis

27 September 2017

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27 September 2017

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Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology

27 September 2017

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IL-10: the master regulator of immunity to infection

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

27 September 2017

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IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

27 September 2017

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

27 September 2017

1 reference

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Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation

27 September 2017

1 reference

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Transforming growth factor-beta and the immune response: implications for anticancer therapy

27 September 2017

1 reference

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Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells

27 September 2017

1 reference

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Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection.

27 September 2017

1 reference

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CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Regulation of immunity by self-reactive T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Stochastic monoallelic expression of IL-10 in T cells

30 May 2018

1 reference

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Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

30 May 2018

1 reference

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Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

28 November 2018

1 reference

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Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

28 November 2018

1 reference

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A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.

28 November 2018

1 reference

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IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Hydrodynamic-based delivery of an interleukin-22-Ig fusion gene ameliorates experimental autoimmune myocarditis in rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Is there an interaction between interleukin-10 and interleukin-22?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755239

Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10

28 November 2018

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12 December 2020

Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

1 reference

12 December 2020

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

1 reference

12 December 2020

Germ-free and barrier-raised TGF beta 1-deficient mice have similar inflammatory lesions

1 reference

12 December 2020

Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma

1 reference

12 December 2020

10.1016/J.COPH.2009.04.008

Identifiers

DOI

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Fatcat

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30 July 2022

release_ota4r4qib5c2zmf76vbi3t34vu

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OpenCitations bibliographic resource ID

160662

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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30 July 2022

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30 July 2022