CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer (Q24642646)

Gene Ontology release 2020-05-02

1 reference

toll like receptor 4

1 reference

Toll like receptor 6

1 reference

cellular response to amyloid-beta

1 reference

CD36 molecule

1 reference

Toll-like receptor 6

1 reference

Myeloid differentiation primary response gene 88

1 reference

Toll-like receptor adaptor molecule 1

1 reference

Toll-like receptor 4

1 reference

7

Katey J Rayner

0 references

Janine M van Gils

Janine M van Gils

4

0 references

Adam Lacy-Hulbert

Adam Lacy-Hulbert

11

0 references

Laurent Boyer

Laurent Boyer

8

0 references

Kathryn J. Moore

Kathryn J Moore

14

0 references

Douglas T Golenbock

13

Douglas T Golenbock

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author name string

Cameron R Stewart

1

0 references

Lynda M Stuart

2

0 references

Kim Wilkinson

3

0 references

Jiusheng Deng

5

0 references

Annett Halle

6

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Ruiqin Zhong

9

0 references

William A Frazier

10

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Joseph El Khoury

on focus list of Wikimedia project

12

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language of work or name

English

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publication date

February 2010

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published in

Nature Immunology

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volume

11

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page(s)

155-61

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issue

2

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ScienceSource

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cites work

Toll-like receptor signalling

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Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

7 April 2017

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Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4

7 April 2017

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Atherosclerosis — An Inflammatory Disease

7 April 2017

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

7 April 2017

1 reference

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Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain

7 April 2017

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

7 April 2017

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CD36 is a sensor of diacylglycerides

7 April 2017

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Oxidized LDL-induced NF-kappa B activation and subsequent expression of proinflammatory genes are defective in monocyte-derived macrophages from CD36-deficient patients

7 April 2017

1 reference

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

7 April 2017

1 reference

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Recognition of microorganisms and activation of the immune response

7 April 2017

1 reference

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A Toll-like receptor 2-integrin beta3 complex senses bacterial lipopeptides via vitronectin.

7 April 2017

1 reference

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Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

27 September 2017

1 reference

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Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

27 September 2017

1 reference

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Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

27 September 2017

1 reference

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Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

27 September 2017

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The inflammasome: a danger sensing complex triggering innate immunity

27 September 2017

1 reference

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Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance

27 September 2017

1 reference

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Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

27 September 2017

1 reference

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A CD36-dependent signaling cascade is necessary for macrophage foam cell formation

27 September 2017

1 reference

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Scavenger receptors in atherosclerosis: beyond lipid uptake

27 September 2017

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Modulation of atherosclerosis in mice by Toll-like receptor 2

27 September 2017

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Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

27 September 2017

1 reference

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Reactive oxygen and nitrogen species in Alzheimer's disease

27 September 2017

1 reference

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Intracellular signalling controlling integrin activation in lymphocytes

27 September 2017

1 reference

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Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

27 September 2017

1 reference

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CD36 mediates the innate host response to beta-amyloid

27 September 2017

1 reference

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Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

27 September 2017

1 reference

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CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils

27 September 2017

1 reference

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Divergent response to LPS and bacteria in CD14-deficient murine macrophages.

27 September 2017

1 reference

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Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation.

27 September 2017

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Immortalization of cloned mouse splenic macrophages with a retrovirus containing the v-raf/mil and v-myc oncogenes

27 September 2017

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Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

30 May 2018

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Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI.

30 May 2018

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Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease.

28 November 2018

1 reference

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Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: pharmacotherapeutic implications

28 November 2018

1 reference

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Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809046

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809046

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809046

Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20037584

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toll-like Receptor 4 Polymorphisms and Atherogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20037584

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inflammatory processes in Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20037584

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.1836

1 reference

Dimensions Publication ID

427958

1037388630

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427958

1 reference

1 reference

1 reference