Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors (Q24642653)

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English	Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors	scientific article

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12 February 2020

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Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors (English)

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12 February 2020

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12 February 2020

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12 February 2020

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John A Peters

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12 February 2020

Michelle A Cooper

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12 February 2020

Matthew R Livesey

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12 February 2020

Jeremy J Lambert

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23 November 2009

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12 February 2020

Journal of Physiology

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12 February 2020

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12 February 2020

Pt 4

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12 February 2020

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12 February 2020

International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update

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7 April 2017

A nomenclature for ligand-gated ion channels

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The 5-HT3B subunit is a major determinant of serotonin-receptor function

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7 April 2017

An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance

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Structure and gating mechanism of the acetylcholine receptor pore

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7 April 2017

The 5-HT3 receptor--the relationship between structure and function

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7 April 2017

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

1 reference

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7 April 2017

Distribution and functional properties of 5-HT3 receptors in the rat hippocampal dentate gyrus: a patch-clamp study

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7 April 2017

Protein interactions involving the gamma2 large cytoplasmic loop of GABA(A) receptors modulate conductance

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27 September 2017

A prokaryotic perspective on pentameric ligand-gated ion channel structure

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Insight in nAChR subtype selectivity from AChBP crystal structures.

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Characterization of the effects of charged residues in the intracellular loop on ion permeation in alpha1 glycine receptor channels.

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Diversity of vertebrate nicotinic acetylcholine receptors

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27 September 2017

The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization

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27 September 2017

On the voltage-dependent Ca2+ block of serotonin 5-HT3 receptors: a critical role of intracellular phosphates

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27 September 2017

Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor.

1 reference

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27 September 2017

Control of cation permeation through the nicotinic receptor channel

1 reference

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27 September 2017

Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop

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27 September 2017

Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors.

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27 September 2017

An energy-efficient gating mechanism in the acetylcholine receptor channel suggested by molecular and Brownian dynamics

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27 September 2017

A role for the beta 1-beta 2 loop in the gating of 5-HT3 receptors.

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27 September 2017

Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor.

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27 September 2017

Role of aspartate 298 in mouse 5-HT3A receptor gating and modulation by extracellular Ca2+.

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27 September 2017

Homology model of the GABAA receptor examined using Brownian dynamics

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27 September 2017

Noncovalent binding between guanidinium and anionic groups: focus on biological- and synthetic-based arginine/guanidinium interactions with phosph[on]ate and sulf[on]ate residues

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27 September 2017

Charge selectivity of the Cys-loop family of ligand-gated ion channels.

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27 September 2017

Ligand-gated ion channels: mechanisms underlying ion selectivity

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27 September 2017

A cluster of novel serotonin receptor 3-like genes on human chromosome 3.

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27 September 2017

A single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptor

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27 September 2017

A cytoplasmic region determines single-channel conductance in 5-HT3 receptors

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27 September 2017

Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E.

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27 September 2017

Ion permeation properties of a cloned human 5-HT3 receptor transiently expressed in HEK 293 cells

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27 September 2017

Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A).

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Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor

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27 September 2017

How pore mouth charge distributions alter the permeability of transmembrane ionic channels

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27 September 2017

Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations

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27 September 2017

Alternate stoichiometries of alpha4beta2 nicotinic acetylcholine receptors

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27 September 2017

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic

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Intracellular domain of nicotinic acetylcholine receptor: the importance of being unfolded.

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Ca2+ ions block and permeate serotonin 5-HT3 receptor channels in rat hippocampal interneurons

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Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors

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Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily

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Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor

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12 December 2020

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