Structures of the G85R variant of SOD1 in familial amyotrophic lateral sclerosis (Q24644037)

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5 January 2020

title

Structures of the G85R variant of SOD1 in familial amyotrophic lateral sclerosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18378676%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

5 January 2020

main subject

cell biology

0 references

0 references

author

Svetlana Antonyuk

2

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5 January 2020

Ashutosh Tiwari

10

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5 January 2020

author name string

Xiaohang Cao

1

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5 January 2020

Sai V Seetharaman

3

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5 January 2020

Lisa J Whitson

4

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5 January 2020

Alexander B Taylor

5

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5 January 2020

Stephen P Holloway

6

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5 January 2020

Richard W Strange

7

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5 January 2020

Peter A Doucette

8

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5 January 2020

Joan Selverstone Valentine

9

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5 January 2020

Lawrence J Hayward

11

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5 January 2020

Shelby Padua

12

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5 January 2020

Jeffrey A Cohlberg

13

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5 January 2020

S Samar Hasnain

14

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5 January 2020

P John Hart

15

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5 January 2020

language of work or name

English

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publication date

31 March 2008

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5 January 2020

number of pages

9

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Journal of Biological Chemistry

inferred from page(s)

published in

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5 January 2020

volume

283

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5 January 2020

page(s)

16169-16177

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5 January 2020

issue

23

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Binding of a single zinc ion to one subunit of copper-zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein

5 January 2020

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The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis

7 April 2017

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7 April 2017

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7 April 2017

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Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

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7 April 2017

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Unraveling the mechanisms involved in motor neuron degeneration in ALS

7 April 2017

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Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models

7 April 2017

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Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology

27 September 2017

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Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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30 May 2018

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30 May 2018

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30 May 2018

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21 January 2018

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Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis.

21 January 2018

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Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant. Insights into the molecular basis for dimer stability

21 January 2018

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MOLREP: an Automated Program for Molecular Replacement

21 January 2018

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Improved Fourier coefficients for maps using phases from partial structures with errors

21 January 2018

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21 January 2018

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Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

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Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126.

21 January 2018

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Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

21 January 2018

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An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

28 November 2018

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The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status

21 January 2018

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12 December 2020

Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models

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12 December 2020

A characterization of copper/zinc superoxide dismutase mutants at position 124. Zinc-deficient proteins

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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An intracellular GSH-peroxidase with a lipid peroxide substrate

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12 December 2020

Identifiers

DOI

10.1074/JBC.M801522200

1 reference

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30 July 2022

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30 July 2022

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30 July 2022