Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes (Q24644120)

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M Elizabeth Hartnett

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John P Atkinson

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Patricia C Giclas

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Johanna M Seddon

Investigative Ophthalmology Visual Science

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language of work or name

English

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publication date

December 2009

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published in

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volume

50

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page(s)

5818-27

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issue

12

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cites work

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A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration

7 April 2017

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CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

7 April 2017

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Drusen complement components C3a and C5a promote choroidal neovascularization

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A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

7 April 2017

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Complement factor H polymorphism in age-related macular degeneration

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Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue

7 April 2017

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Systemic complement activation in age-related macular degeneration

7 April 2017

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HTRA1 promoter polymorphism in wet age-related macular degeneration

7 April 2017

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Complement factor H variant increases the risk of age-related macular degeneration

7 April 2017

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Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization

7 April 2017

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An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

7 April 2017

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Complement factor H polymorphism and age-related macular degeneration

7 April 2017

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Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables

7 April 2017

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Dual role of complement in adipose tissue.

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Complement activation fragment Bb in early pregnancy and spontaneous preterm birth

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Acylation-stimulating protein deficiency and altered adipose tissue in alternative complement pathway knockout mice

27 September 2017

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Variation in complement factor 3 is associated with risk of age-related macular degeneration

27 September 2017

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Estimation of systemic complement C3 activity in age-related macular degeneration

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Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium

27 September 2017

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A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

Association between reproductive and hormonal factors and age-related maculopathy in postmenopausal women

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

Acylation stimulating protein but not complement C3 associates with metabolic syndrome components in Chinese children and adolescents

27 September 2017

1 reference

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C-reactive protein and homocysteine are associated with dietary and behavioral risk factors for age-related macular degeneration

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

Evaluation of the clinical age-related maculopathy staging system

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

Association between C-reactive protein and age-related macular degeneration.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826794

Generation of C5a in the absence of C3: a new complement activation pathway

28 November 2018

1 reference

12 December 2020

CFH gene variant, Y402H, and smoking, body mass index, environmental associations with advanced age-related macular degeneration

1 reference

12 December 2020

Inflammatory proteins are related to total and abdominal adiposity in a healthy adolescent population: the AVENA Study

1 reference

12 December 2020

Progression of age-related macular degeneration: association with body mass index, waist circumference, and waist-hip ratio

1 reference

12 December 2020

Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration

1 reference

12 December 2020

Levels of C3 in patients with severe, morbid and extreme obesity: its relationship to insulin resistance and different cardiovascular risk factors

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.09-3928

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1056604

1056604

1 reference

1 reference

1 reference