Neural KCNQ (Kv7) channels (Q24644947)

British Journal of Pharmacology

Europe PubMed Central

title

Neural KCNQ (Kv7) channels (English)

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author name string

David A Brown

series ordinal

1

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Gayle M Passmore

series ordinal

2

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language of work or name

English

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publication date

April 2009

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published in

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volume

156

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issue

8

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page(s)

1185-95

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cites work

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27 September 2017

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Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants

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27 September 2017

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Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq.

27 September 2017

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27 September 2017

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27 September 2017

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Neuronal KCNQ potassium channels: physiology and role in disease.

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Molecular basis for differential sensitivity of KCNQ and I(Ks) channels to the cognitive enhancer XE991.

27 September 2017

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30 May 2018

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30 May 2018

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Voltage-clamp analysis of muscarinic excitation in hippocampal neurons

30 May 2018

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Closure of potassium M-channels by muscarinic acetylcholine-receptor stimulants requires a diffusible messenger

30 May 2018

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In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models

30 May 2018

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Retigabine reduces the excitability of unmyelinated peripheral human axons

28 November 2018

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Spike Ca2+ influx upmodulates the spike afterdepolarization and bursting via intracellular inhibition of KV7/M channels

28 November 2018

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The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats

28 November 2018

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Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety.

28 November 2018

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The neuronal KCNQ channel opener retigabine inhibits locomotor activity and reduces forebrain excitatory responses to the psychostimulants cocaine, methylphenidate and phencyclidine.

28 November 2018

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PIP(2)-dependent inhibition of M-type (Kv7.2/7.3) potassium channels: direct on-line assessment of PIP(2) depletion by Gq-coupled receptors in single living neurons.

28 November 2018

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Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.

28 November 2018

1 reference

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The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.

28 November 2018

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Probing the regulation of M (Kv7) potassium channels in intact neurons with membrane-targeted peptides.

28 November 2018

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Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels.

28 November 2018

1 reference

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KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697739

Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.

28 November 2018

1 reference

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Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels.

28 November 2018

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The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate

28 November 2018

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Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.

28 November 2018

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Meclofenamic acid and diclofenac, novel templates of KCNQ2/Q3 potassium channel openers, depress cortical neuron activity and exhibit anticonvulsant properties

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697739

KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697739

The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697739

KCNQ2 is a nodal K+ channel.

28 November 2018

1 reference

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KCNQ/M currents in sensory neurons: significance for pain therapy.

28 November 2018

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Effect of the KCNQ potassium channel opener retigabine on single KCNQ2/3 channels expressed in CHO cells

28 November 2018

1 reference

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PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697739

The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic pain

28 November 2018

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Molecular correlates of the M-current in cultured rat hippocampal neurons

28 November 2018

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Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis

28 November 2018

1 reference

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Effects of the anticonvulsant retigabine on cultured cortical neurons: changes in electroresponsive properties and synaptic transmission

28 November 2018

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Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine.

28 November 2018

1 reference

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D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.

28 November 2018

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Potassium currents in rat prevertebral and paravertebral sympathetic neurones: control of firing properties.

28 November 2018

1 reference

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The therapeutic potential of neuronal K V 7 (KCNQ) channel modulators: an update

28 November 2018

1 reference

12 December 2020

Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

1 reference

12 December 2020

Evidence for the existence of three types of potassium channels in the frog Ranvier node membrane

1 reference

12 December 2020

Retigabine-induced population primary afferent hyperpolarisation in vitro

1 reference

12 December 2020

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2009.00111.X

1 reference

7 January 2021

inferred from DOI database lookup

Two components of muscarine-sensitive membrane current in rat sympathetic neurones.

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2009.00111.X

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1111/J.1476-5381.2009.00111.X

1 reference

1412972

1412972

1 reference

1 reference

1 reference