The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction (Q24645508)

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English	The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction	scientific article

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scholarly article

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The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction (English)

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author name string

R Müller

1

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J Wienands

2

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M Reth

3

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language of work or name

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publication date

18 July 2000

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Proceedings of the National Academy of Sciences of the United States of America

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97

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8451-4

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15

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SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

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7 April 2017

Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide

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7 April 2017

BLNK: a central linker protein in B cell activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

Serine phosphorylation and negative regulation of Stat3 by JNK

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

BASH, a novel signaling molecule preferentially expressed in B cells of the bursa of Fabricius

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7 April 2017

Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

Tyrosine phosphorylation and Fcgamma receptor-mediated phagocytosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

7 April 2017

Structural features of heterotrimeric G-protein-coupled receptors and their modulatory proteins

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27 September 2017

G-protein coupled receptor kinases as modulators of G-protein signalling

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27 September 2017

Alpha4 protein as a common regulator of type 2A-related serine/threonine protein phosphatases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Ig receptor binding protein 1 (alpha4) is associated with a rapamycin-sensitive signal transduction in lymphocytes through direct binding to the catalytic subunit of protein phosphatase 2A.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

A tyrosine-based signal present in Ig alpha mediates B cell receptor constitutive internalization.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Evidence for a preformed transducer complex organized by the B cell antigen receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

New simplified molecular design for functional T cell receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

The alpha/beta sheath and its cytoplasmic tyrosines are required for signaling by the B-cell antigen receptor but not for capping or for serine/threonine-kinase recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Activation and serine phosphorylation of the p56lck protein tyrosine kinase in response to antigen receptor cross-linking in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Molecular cloning of a cDNA clone encoding a phosphoprotein component related to the Ig receptor-mediated signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Immunoglobulin gene expression in transformed lymphoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

27 September 2017

Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

30 May 2018

Antigen receptor signaling gives lymphocytes a long life

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

30 May 2018

The complexity of signaling pathways activated by the BCR.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

30 May 2018

Binding affinities of the SH2 domains of ZAP-70, p56lck and Shc to the zeta chain ITAMs of the T-cell receptor determined by surface plasmon resonance.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

30 May 2018

Molecular components of the B-cell antigen receptor complex of the IgM class.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

30 May 2018

Regulation of basal tyrosine phosphorylation of the B cell antigen receptor complex by the protein tyrosine phosphatase, CD45

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

30 May 2018

Characterization of molecular components associated with surface immunoglobulin M in human B lymphocytes: presence of tyrosine and serine/threonine protein kinases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

30 May 2018

Antigen receptor tail clue.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26968

19 June 2018

New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL)

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn.

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https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

Analysis of immunoreceptor tyrosine-based activation motif (ITAM) binding to ZAP-70 by surface plasmon resonance

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

Ig-α Cytoplasmic Truncation Renders Immature B Cells More Sensitive to Antigen Contact

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https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

Grabbing phosphoproteins

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https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors

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https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

In vitro characterization of major ligands for Src homology 2 domains derived from protein tyrosine kinases, from the adaptor protein SHC and from GTPase-activating protein in Ramos B cells

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

Differential binding activity of ARH1/TAM motifs

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

Identification of two distinct phosphoproteins as components of the human B cell antigen receptor complex

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https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

Biochemical evidence that the phosphorylated tyrosines, serines, and threonines on the aggregated high affinity receptor for IgE are in the immunoreceptor tyrosine-based activation motifs

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

A negative regulatory role for Ig-alpha during B cell development

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https://api.crossref.org/works/10.1073%2FPNAS.97.15.8451

21 January 2018

The role of serine/threonine phosphorylation in hematopoietic cytokine receptor signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10900006

12 December 2020

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Identifiers

10.1073/PNAS.97.15.8451

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2000PNAS...97.8451M

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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