Get to grips: steering local actin dynamics with IQGAPs (Q24645636)

Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation

Europe PubMed Central

title

Get to grips: steering local actin dynamics with IQGAPs (English)

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Robert Grosse

2

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author name string

Dominique T Brandt

series ordinal

1

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language of work or name

English

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publication date

November 2007

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published in

EMBO Reports

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volume

8

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issue

11

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page(s)

1019-23

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cites work

1 reference

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IQGAP1 modulates activation of B-Raf

7 April 2017

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Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.

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IQGAP1 is a scaffold for mitogen-activated protein kinase signaling

7 April 2017

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IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner

7 April 2017

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IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization

7 April 2017

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IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments

7 April 2017

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The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases

7 April 2017

1 reference

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IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs

7 April 2017

1 reference

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Identification of a human rasGAP-related protein containing calmodulin-binding motifs

7 April 2017

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Role of formins in actin assembly: nucleation and barbed-end association

7 April 2017

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The multiple roles of Cyk1p in the assembly and function of the actomyosin ring in budding yeast

7 April 2017

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Sequential assembly of myosin II, an IQGAP-like protein, and filamentous actin to a ring structure involved in budding yeast cytokinesis

7 April 2017

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IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients

7 April 2017

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IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth

7 April 2017

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Staying in shape with formins

7 April 2017

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IQGAP1: a key regulator of adhesion and migration

7 April 2017

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Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration

7 April 2017

1 reference

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Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170

7 April 2017

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ROCK and Dia have opposing effects on adherens junctions downstream of Rho

7 April 2017

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The mechanism for regulation of the F-actin binding activity of IQGAP1 by calcium/calmodulin

7 April 2017

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Recruitment of cortexillin into the cleavage furrow is controlled by Rac1 and IQGAP-related proteins

7 April 2017

1 reference

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IQGAP1 and calmodulin modulate E-cadherin function

7 April 2017

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Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion

7 April 2017

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Cytokinesis: IQGAPs find a function

7 April 2017

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Regulation of cross-linking of actin filament by IQGAP1, a target for Cdc42

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2247391

Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1

7 April 2017

1 reference

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Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility

7 April 2017

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Regulation of actin filament assembly by Arp2/3 complex and formins

7 April 2017

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Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1.

7 April 2017

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IQGAP1 binds Rap1 and modulates its activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2247391

IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2247391

IQGAP1 stimulates actin assembly through the N-WASP-Arp2/3 pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2247391

Assembly of the cytokinetic contractile ring from a broad band of nodes in fission yeast

27 September 2017

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IQGAP1 in cellular signaling: bridging the GAP.

27 September 2017

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A role for mammalian diaphanous-related formins in complement receptor (CR3)-mediated phagocytosis in macrophages

27 September 2017

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Tumor cell pseudopodial protrusions. Localized signaling domains coordinating cytoskeleton remodeling, cell adhesion, glycolysis, RNA translocation, and protein translation

27 September 2017

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Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of rho-GTPase regulator

27 September 2017

1 reference

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EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

27 September 2017

1 reference

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Actin filament binding by a monomeric IQGAP1 fragment with a single calponin homology domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2247391

Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2247391

An IQGAP‐like protein is involved in actin assembly together with Cdc42 in the sea urchin egg

27 September 2017

1 reference

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Involvement of the Arp2/3 complex in phagocytosis mediated by FcgammaR or CR3.

27 September 2017

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Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

27 September 2017

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Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2247391

T cell responses in mammalian diaphanous-related formin mDia1 knock-out mice.

27 September 2017

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Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body

21 January 2018

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Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

21 January 2018

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Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts

21 January 2018

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Counting cytokinesis proteins globally and locally in fission yeast.

21 January 2018

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IQGAP2 is required for the cadherin-mediated cell-to-cell adhesion in Xenopus laevis embryos.

21 January 2018

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Localization of two IQGAPs in cultured cells and early embryos of Xenopus laevis

21 January 2018

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PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression and diffuse expression pattern of IQGAP1 at invasion fronts are independent prognostic parameters in ovarian carcinomas

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PubMed

https://pubmed.ncbi.nlm.nih.gov/17972901