Discovery of a small-molecule inhibitor of {beta}-1,6-glucan synthesis (Q24645700)

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Kazuhiko Someya

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Masato Hata

3

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Ryohei Nakajima

4

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Makoto Takemura

Antimicrobial Agents and Chemotherapy

5

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language of work or name

English

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publication date

February 2009

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published in

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volume

53

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issue

2

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page(s)

670-7

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cites work

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Characterization of the yeast (1-->6)-beta-glucan biosynthetic components, Kre6p and Skn1p, and genetic interactions between the PKC1 pathway and extracellular matrix assembly

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Emergence of a Candida krusei isolate with reduced susceptibility to caspofungin during therapy

27 September 2017

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Invasive fungal infections: a review of epidemiology and management options

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Potential role of aerosolized amphotericin B formulations in the prevention and adjunctive treatment of invasive fungal infections

27 September 2017

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Deletion of the CaBIG1 gene reduces beta-1,6-glucan synthesis, filamentation, adhesion, and virulence in Candida albicans

27 September 2017

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Therapy of systemic fungal infections: a pharmacologic perspective

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KRE5 gene null mutant strains of Candida albicans are avirulent and have altered cell wall composition and hypha formation properties

27 September 2017

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Management of invasive candidiasis in critically ill patients

27 September 2017

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Changing strategies for the management of invasive fungal infections

27 September 2017

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The global epidemiology of invasive Candida infections--is the tide turning?

27 September 2017

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Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway.

27 September 2017

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Isolation of Candida glabrata homologs of the Saccharomyces cerevisiae KRE9 and KNH1 genes and their involvement in cell wall beta-1,6-glucan synthesis.

27 September 2017

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The Candida albicans KRE9 gene is required for cell wall beta-1, 6-glucan synthesis and is essential for growth on glucose

27 September 2017

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Cell wall architecture in yeast: new structure and new challenges

27 September 2017

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Interpretation of trailing endpoints in antifungal susceptibility testing by the National Committee for Clinical Laboratory Standards method.

27 September 2017

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Lipopeptide inhibitors of fungal glucan synthase

27 September 2017

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Isolation of the Candida albicans homologs of Saccharomyces cerevisiae KRE6 and SKN1: expression and physiological function

27 September 2017

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Comparison of cell wall proteins of Saccharomyces cerevisiae as anchors for cell surface expression of heterologous proteins

27 September 2017

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SKN1 and KRE6 define a pair of functional homologs encoding putative membrane proteins involved in beta-glucan synthesis

27 September 2017

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Nikkomycin Z is a specific inhibitor of Saccharomyces cerevisiae chitin synthase isozyme Chs3 in vitro and in vivo

27 September 2017

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Review: cell wall assembly in yeast

27 September 2017

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Glycosyl phosphatidylinositol-dependent cross-linking of alpha-agglutinin and beta 1,6-glucan in the Saccharomyces cerevisiae cell wall.

27 September 2017

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Use of a colorimetric system for yeast susceptibility testing

27 September 2017

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Papulacandins, a new family of antibiotics with antifungal activity, I. Fermentation, isolation, chemical and biological characterization of papulacandins A, B, C, D and E.

27 September 2017

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Yeast KRE genes provide evidence for a pathway of cell wall beta-glucan assembly

27 September 2017

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Testing the efficacy of RNA interference constructs in Aspergillus fumigatus.

30 May 2018

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Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions

28 November 2018

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Inductions of germ tube and hyphal formations are controlled by mRNA synthesis inhibitor in Candida albicans

28 November 2018

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The ω‐site sequence of glycosylphosphatidylinositol‐anchored proteins in Saccharomyces cerevisiae can determine distribution between the membrane and the cell wall

28 November 2018

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The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants.

28 November 2018

1 reference

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28 November 2018

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28 November 2018

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Glucosylation of chimeric proteins in the cell wall of Saccharomyces cerevisiae

28 November 2018

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Adhesive and Mammalian Transglutaminase Substrate Properties of Candida albicans Hwp1

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