Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements (Q24646249)

5

1 reference

ORCID Public Data File 2021

Bjørn Olav Brandsdal

object named as

Bjørn Olav Brandsdal

2

1 reference

ORCID Public Data File 2021

author name string

Hanna-Kirsti Schrøder Leiros

1

0 references

Ole Andreas Andersen

3

0 references

Vibeke Os

4

0 references

Ronny Helland

6

0 references

Nils Peder Willassen

8

0 references

Arne O Smalås

Crystal structure and nucleotide sequence of an anionic trypsin from chum salmon (Oncorhynchus keta) in comparison with Atlantic salmon (Salmo salar) and bovine trypsin

9

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language of work or name

English

0 references

publication date

April 2004

0 references

published in

Protein Science

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volume

13

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issue

4

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page(s)

1056-70

0 references

cites work

1 reference

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Atomic resolution structures of trypsin provide insight into structural radiation damage

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X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates

7 April 2017

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Crystal structures of human factor Xa complexed with potent inhibitors

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Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin

7 April 2017

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The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI

7 April 2017

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High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes

7 April 2017

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The crystal structure of anionic salmon trypsin in complex with bovine pancreatic trypsin inhibitor

7 April 2017

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Structure of a non-psychrophilic trypsin from a cold-adapted fish species

7 April 2017

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Design of potent selective zinc-mediated serine protease inhibitors

7 April 2017

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Cold adaption of enzymes: structural comparison between salmon and bovine trypsins

7 April 2017

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Prediction of new serine proteinase inhibitors

7 April 2017

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SHELXL: high-resolution refinement

7 April 2017

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The CCP4 suite: programs for protein crystallography

7 April 2017

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

7 April 2017

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On the size of the active site in proteases. I. Papain

7 April 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

7 April 2017

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Free energy calculations and ligand binding

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Ligand binding affinities from MD simulations.

27 September 2017

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Computational analysis of binding of P1 variants to trypsin.

27 September 2017

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27 September 2017

Cold adapted enzymes.

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Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region

27 September 2017

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Trypsin: a case study in the structural determinants of enzyme specificity

27 September 2017

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Serine proteinases from cold-adapted organisms

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What determines the van der Waals coefficient beta in the LIE (linear interaction energy) method to estimate binding free energies using molecular dynamics simulations?

27 September 2017

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Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold

30 May 2018

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Purification and characterization of trypsin from the poikilotherm Gadus morhua

30 May 2018

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Converting trypsin to chymotrypsin: the role of surface loops

30 May 2018

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Structure of anionic salmon trypsin in a second crystal form.

30 May 2018

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Electrostatic effects play a central role in cold adaptation of trypsin

28 November 2018

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Electrostatics of mesophilic and psychrophilic trypsin isoenzymes: qualitative evaluation of electrostatic differences at the substrate binding site.

28 November 2018

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Structural comparison of psychrophilic and mesophilic trypsins. Elucidating the molecular basis of cold-adaptation

28 November 2018

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Q: a molecular dynamics program for free energy calculations and empirical valence bond simulations in biomolecular systems.

28 November 2018

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A new method for predicting binding affinity in computer-aided drug design

28 November 2018

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12 December 2020

Converting trypsin to chymotrypsin: residue 172 is a substrate specificity determinant

1 reference

12 December 2020

Anionic trypsin from chum salmon: activity with p-amidinophenyl ester and comparison with bovine and Streptomyces griseus trypsins

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12 December 2020

Converting trypsin to elastase: substitution of the S1 site and adjacent loops reconstitutes esterase specificity but not amidase activity

1 reference

12 December 2020

Interscaffolding additivity: binding of P1 variants of bovine pancreatic trypsin inhibitor to four serine proteases

1 reference

12 December 2020

Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity

1 reference

12 December 2020

Temperature and pH sensitivity of trypsins from Atlantic salmon (Salmo salar) in comparison with bovine and porcine trypsin

1 reference

12 December 2020