The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase (Q24646329)

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English	The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase	scientific article

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9770455%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9770455%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Escherichia coli

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angiogenesis inhibitor

1 reference

based on heuristic

inferred from title

Allen M Orville

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9770455%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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W T Lowther

1

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5 December 2019

D A McMillen

2

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5 December 2019

B W Matthews

4

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5 December 2019

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1 October 1998

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5 December 2019

Proceedings of the National Academy of Sciences of the United States of America

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5 December 2019

95

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5 December 2019

21

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5 December 2019

12153-12157

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5 December 2019

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

1 reference

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7 April 2017

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

1 reference

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7 April 2017

Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes

1 reference

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7 April 2017

Methionine aminopeptidase gene of Escherichia coli is essential for cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22800

7 April 2017

Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli

1 reference

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7 April 2017

Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme

1 reference

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7 April 2017

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

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7 April 2017

Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22800

7 April 2017

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

1 reference

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7 April 2017

Angiogenesis in cancer, vascular, rheumatoid and other disease

1 reference

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7 April 2017

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1 reference

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7 April 2017

Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin.

1 reference

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27 September 2017

Cobalt as probe and label of proteins

1 reference

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27 September 2017

Sequence and structure comparison suggest that methionine aminopeptidase, prolidase, aminopeptidase P, and creatinase share a common fold

1 reference

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27 September 2017

Clinical trials of antiangiogenic agents

1 reference

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27 September 2017

Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis

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27 September 2017

High spin cobalt(II) as a probe for the investigation of metalloproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22800

27 September 2017

Processing of the initiation methionine from proteins: properties of the Escherichia coli methionine aminopeptidase and its gene structure

1 reference

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27 September 2017

pepM is an essential gene in Salmonella typhimurium

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27 September 2017

The eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells.

1 reference

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27 September 2017

Angiogenesis and tumor metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22800

30 May 2018

TNP-470 is an effective antimicrosporidial agent

1 reference

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30 May 2018

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance

1 reference

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30 May 2018

Clinical trials of antiangiogenic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22800

30 May 2018

N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families

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21 January 2018

A cancer therapy resistant to resistance

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Short Enantioselective Synthesis of (-)-Ovalicin, a Potent Inhibitor of Angiogenesis, Using Substrate-Enhanced Catalytic Asymmetric Dihydroxylation

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.21.12153

21 January 2018

Fumagillin analog in the treatment of Kaposi's sarcoma: a phase I AIDS Clinical Trial Group study. AIDS Clinical Trial Group No. 215 Team

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A protease assay via precolumn derivatization and high-performance liquid chromatography

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Crystallization and preliminary X-ray analysis of methionine aminopeptidase from the hyperthermophilic bacterium Pyrococcus furiosus

1 reference

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Evidence that two zinc fingers in the methionine aminopeptidase from Saccharomyces cerevisiae are important for normal growth

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.21.12153

21 January 2018

Identifiers

10.1073/PNAS.95.21.12153

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9770455%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1998PNAS...9512153L

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9770455%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9770455%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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