A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model (Q24646533)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18534670%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model (English)

1 reference

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8 January 2020

main subject

clinical chemistry

0 references

pimavanserin tartrate

1 reference

ChEBI release 2020-05-28

1 reference

1 reference

9

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8 January 2020

author name string

Kimberly E Vanover

1

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8 January 2020

Adrienne J Betz

2

1 reference

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8 January 2020

Suzanne M Weber

3

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8 January 2020

Francesco Bibbiani

4

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8 January 2020

Aiste Kielaite

5

1 reference

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8 January 2020

David M Weiner

6

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8 January 2020

Robert E Davis

7

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8 January 2020

Thomas N Chase

8

1 reference

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8 January 2020

language of work or name

English

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publication date

1 October 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18534670%20AND%20SRC:MED&resulttype=core&format=json

Pharmacology, Biochemistry and Behavior

8 January 2020

published in

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8 January 2020

volume

90

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8 January 2020

issue

4

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8 January 2020

page(s)

540-544

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5-hydroxytryptamine2A receptor inverse agonists as antipsychotics

8 January 2020

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1 reference

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Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist

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Dopamine agonists suppress cholinomimetic-induced tremulous jaw movements in an animal model of Parkinsonism: tremorolytic effects of pergolide, ropinirole and CY 208-243.

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Local injections of the 5-hydroxytryptamine antagonist mianserin into substantia nigra pars reticulata block tremulous jaw movements in rats: studies with a putative model of Parkinsonian tremor

27 September 2017

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Activation of 5-HT(1A) but not 5-HT(1B) receptors attenuates an increase in extracellular dopamine derived from exogenously administered L-DOPA in the striatum with nigrostriatal denervation

27 September 2017

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27 September 2017

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30 May 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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Effect of 5-HT1A and 5-HT2A/2C receptor modulation on neuroleptic-induced vacuous chewing movements

28 November 2018

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28 November 2018

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12 December 2020

Low dosage clozapine effects on L-dopa induced dyskinesias in parkinsonian patients

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12 December 2020

The pharmacological characterisation of pilocarpine-induced purposeless chewing behaviour in the rat

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12 December 2020

Clozapine in idiopathic Parkinson's disease

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12 December 2020

Effects of acute and repeated clozapine injections on cholinomimetic-induced vacuous jaw movements

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12 December 2020

10.1016/J.PBB.2008.04.010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18534670%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18534670%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference