Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOS (Q24646851)

2

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D E Afar

3

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M Shibuya

4

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O N Witte

5

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T E Smithgall

Molecular and Cellular Biology

6

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language of work or name

English

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publication date

February 1995

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published in

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volume

15

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issue

2

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page(s)

835-42

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cites work

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The FER gene is evolutionarily conserved and encodes a widely expressed member of the FPS/FES protein-tyrosine kinase family

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rac, a novel ras-related family of proteins that are botulinum toxin substrates

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K562 leukemia cells transfected with the human c-fes gene acquire the ability to undergo myeloid differentiation

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Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP)

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Bcr encodes a GTPase-activating protein for p21rac

7 April 2017

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Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

7 April 2017

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The BCR gene encodes a novel serine/threonine kinase activity within a single exon

7 April 2017

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Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries

7 April 2017

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A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction

7 April 2017

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

7 April 2017

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

7 April 2017

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SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

7 April 2017

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

7 April 2017

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A multipotential leukemia cell line (K-562) of human origin

7 April 2017

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Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

7 April 2017

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Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

7 April 2017

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A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr

7 April 2017

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BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

7 April 2017

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A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs

7 April 2017

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Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

7 April 2017

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

7 April 2017

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BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

7 April 2017

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A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

27 September 2017

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Phosphorylation of the ras GTPase-activating protein (GAP) by the p93c-fes protein-tyrosine kinase in vitro and formation of GAP-fes complexes via an SH2 domain-dependent mechanism.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3.

27 September 2017

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Evidence that the phl gene encodes a 160,000-dalton phosphoprotein with associated kinase activity

27 September 2017

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

27 September 2017

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Non-catalytic domains of cytoplasmic protein-tyrosine kinases: regulatory elements in signal transduction

27 September 2017

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Construction and biological analysis of deletion mutants of Fujinami sarcoma virus: 5'-fps sequence has a role in the transforming activity

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Chicken myeloid stem cells infected by retroviruses carrying the v-fps oncogene do not require exogenous growth factors to differentiate in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

BCR-ABL tyrosine kinase is autophosphorylated or transphosphorylates P160 BCR on tyrosine predominantly within the first BCR exon

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Tyrosine phosphorylation of P160 BCR by P210 BCR-ABL.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Resistance of NIH3T3 cells to v-fes transformation induced by a dominant negative H-ras mutant

30 May 2018

1 reference

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Erythropoietin induces tyrosine phosphorylation and kinase activity of the c-fps/fes proto-oncogene product in human erythropoietin-responsive cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Transforming genes of avian (v-ƒps) and mammalian (v-ƒes) retroviruses correspond to a common cellular locus

30 May 2018

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30 May 2018

1 reference

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Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231961

Identification of the differentiation-associated p93 tyrosine protein kinase of HL-60 leukemia cells as the product of the human c-fes locus and its expression in myelomonocytic cells.

30 May 2018

1 reference

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30 May 2018

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Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

30 May 2018

1 reference

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30 May 2018

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30 May 2018

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12 December 2020

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

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12 December 2020

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

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12 December 2020

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

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12 December 2020