Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation (Q24646956)

2

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Daniel P Morris

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Michael P Smith

4

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Raphael J Louie

5

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Debra A Schwinn

alpha(1)-adrenoceptor subtypes differentially couple to growth promotion and inhibition in Chinese hamster ovary cells

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language of work or name

English

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publication date

July 2007

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published in

FASEB Journal

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volume

21

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issue

9

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page(s)

1979-93

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cites work

1 reference

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A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

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Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3

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Cloning and characterization of the mouse alpha1C/A-adrenergic receptor gene and analysis of an alpha1C promoter in cardiac myocytes: role of an MCAT element that binds transcriptional enhancer factor-1 (TEF-1)

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The epigenetic progenitor origin of human cancer

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De novo methylation, long-term promoter silencing, methylation patterns in the human genome, and consequences of foreign DNA insertion.

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Replication and translation of epigenetic information.

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The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.

27 September 2017

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Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation

27 September 2017

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Coordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcription

27 September 2017

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Differential cardiac gene expression during cardiopulmonary bypass: ischemia-independent upregulation of proinflammatory genes.

27 September 2017

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Evidence that phosphorylation of the RNA polymerase II carboxyl-terminal repeats is similar in yeast and humans.

27 September 2017

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Insensitivity to transforming growth factor-beta results from promoter methylation of cognate receptors in human prostate cancer cells (LNCaP).

27 September 2017

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Imprinted X inactivation and reprogramming in the preimplantation mouse embryo.

27 September 2017

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MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.

27 September 2017

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Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes

27 September 2017

1 reference

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Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter

27 September 2017

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Recent advances in α1-adrenoceptor pharmacology

27 September 2017

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Genetic Profiling of α1-Adrenergic Receptor Subtypes by Oligonucleotide Microarrays: Coupling to Interleukin-6 Secretion but Differences in STAT3 Phosphorylation and gp-130

27 September 2017

1 reference

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alpha 1-Adrenergic receptor subtypes differentially control the cell cycle of transfected CHO cells through a cAMP-dependent mechanism involving p27Kip1.

27 September 2017

1 reference

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Regulation of the activity of Sp1-related transcription factors.

27 September 2017

1 reference

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Tamsulosin: a review of its pharmacology and therapeutic efficacy in the management of lower urinary tract symptoms

27 September 2017

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Modulation of bladder alpha1-adrenergic receptor subtype expression by bladder outlet obstruction

27 September 2017

1 reference

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Alpha 1-adrenergic receptor regulation: basic science and clinical implications

27 September 2017

1 reference

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Immortalization of a human prostate stromal cell line using a recombinant retroviral approach

27 September 2017

1 reference

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CpG methylation as a mechanism for the regulation of E2F activity

27 September 2017

1 reference

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alpha1-adrenergic receptors in the lower urinary tract and vascular bed: potential role for the alpha1d subtype in filling symptoms and effects of ageing on vascular expression.

27 September 2017

1 reference

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Subtype specific regulation of human vascular alpha(1)-adrenergic receptors by vessel bed and age.

27 September 2017

1 reference

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Cloning, cell-type specificity, and regulatory function of the mouse alpha(1B)-adrenergic receptor promoter.

27 September 2017

1 reference

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Methyl-CpG-binding protein MeCP2 represses Sp1-activated transcription of the human leukosialin gene when the promoter is methylated

27 September 2017

1 reference

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Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site

27 September 2017

1 reference

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Induction of transforming growth factor-beta receptor type II expression in estrogen receptor-positive breast cancer cells through SP1 activation by 5-aza-2'-deoxycytidine

27 September 2017

1 reference

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Alpha1D-adrenergic receptors and mitogen-activated protein kinase mediate increased protein synthesis by arterial smooth muscle

27 September 2017

1 reference

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Effects of DNA methylation on DNA-binding proteins and gene expression.

27 September 2017

1 reference

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Vasoactive mediators and splanchnic perfusion.

27 September 2017

1 reference

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Isolation and characterization of the gene encoding the rat alpha 1B adrenergic receptor

27 September 2017

1 reference

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Transcription from TATA-less promoters: dihydrofolate reductase as a model.

27 September 2017

1 reference

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A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation

27 September 2017

1 reference

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Transcription of the rat alpha 1B adrenergic receptor gene in liver is controlled by three promoters

27 September 2017

1 reference

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Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy

27 September 2017

1 reference

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Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.

27 September 2017

1 reference

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Distribution and function of peripheral alpha-adrenoceptors in the cardiovascular system

27 September 2017

1 reference

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Triplex formation prevents Sp1 binding to the dihydrofolate reductase promoter

27 September 2017

1 reference

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Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein

27 September 2017

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Expression of alpha 1-adrenergic receptor subtype mRNA in rat tissues and human SK-N-MC neuronal cells: implications for alpha 1-adrenergic receptor subtype classification.

27 September 2017

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Cellular trafficking of human alpha1a-adrenergic receptors is continuous and primarily agonist-independent

27 September 2017

1 reference

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Cloning and characterization of the rat alpha 1a-adrenergic receptor gene promoter. Demonstration of cell specificity and regulation by hypoxia

30 May 2018

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Reciprocal regulation of beta(1)-adrenergic receptor gene transcription by Sp1 and early growth response gene 1: induction of EGR-1 inhibits the expression of the beta(1)-adrenergic receptor gene

30 May 2018

1 reference

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Platelet-derived growth factor-BB inhibits rat alpha1D-adrenergic receptor gene expression in vascular smooth muscle cells by inducing AP-2-like protein binding to alpha1D proximal promoter region

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279228

How does DNA methylation repress transcription?

30 May 2018

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Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region

30 May 2018

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Generality of a functional initiator consensus sequence

30 May 2018

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Sp1 elements protect a CpG island from de novo methylation

30 May 2018

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Acute mesenteric ischemia after cardiopulmonary bypass

30 May 2018

1 reference

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Epigenetic regulation of metallothionein-i gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins

30 May 2018

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Release of methyl CpG binding proteins and histone deacetylase 1 from the Estrogen receptor alpha (ER) promoter upon reactivation in ER-negative human breast cancer cells

28 November 2018

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28 November 2018

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28 November 2018

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Targeted alpha(1A)-adrenergic receptor overexpression induces enhanced cardiac contractility but not hypertrophy

28 November 2018

1 reference

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Long-term, open-label, phase III multicenter study of tamsulosin in benign prostatic hyperplasia

28 November 2018

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Sp1-mediated transcriptional activation from the dominant promoter of the rat alpha1B adrenergic receptor gene in DDT1MF-2 cells

28 November 2018

1 reference

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Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C.

28 November 2018

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Localization of mRNA for three distinct alpha 1-adrenergic receptor subtypes in human tissues: implications for human alpha-adrenergic physiology

28 November 2018

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Cloning of the rat alpha 1C-adrenergic receptor from cardiac myocytes. alpha 1C, alpha 1B, and alpha 1D mRNAs are present in cardiac myocytes but not in cardiac fibroblasts.

28 November 2018

1 reference

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Different alpha-adrenoceptor subtypes mediate constriction of arterioles and venules

28 November 2018

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Evidence for an age-dependent functional expression of alpha 1D-adrenoceptors in the rat vasculature

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Alpha1-adrenergic receptor subtypes in human detrusor

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