BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours (Q24647085)

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N Pore

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F Docquier

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Z K Abdullaev

4

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I Chernukhin

5

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G-X Kita

6

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S Rai

7

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M Smart

8

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D Farrar

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S Pack

10

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V Lobanenkov

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E Klenova

British Journal of Cancer

12

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language of work or name

English

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publication date

12 February 2008

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published in

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volume

98

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issue

3

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page(s)

571-9

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cites work

Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors

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BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

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The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer

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Loss of imprinting and cancer

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The potential of BORIS detected in the leukocytes of breast cancer patients as an early marker of tumorigenesis

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GATA5 activation of the progesterone receptor gene promoter in breast cancer cells is influenced by the +331G/A polymorphism.

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Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes

27 September 2017

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Expression of cancer-testis antigens in hepatocellular carcinoma

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PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen?

27 September 2017

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Monoclonal antibody MA454 reveals a heterogeneous expression pattern of MAGE-1 antigen in formalin-fixed paraffin embedded lung tumours

27 September 2017

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CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms

27 September 2017

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A post-genomic challenge: learning to read patterns of protein synthesis.

27 September 2017

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A cell line (HBL-100) established from human breast milk

21 January 2018

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Y-box factor YB-1 predicts drug resistance and patient outcome in breast cancer independent of clinically relevant tumor biologic factors HER2, uPA and PAI-1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.BJC.6604181

Cancer/testis (CT) antigens - a new link between gametogenesis and cancer

21 January 2018

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[Estrogen receptors and the mammary gland]

28 November 2018

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12 December 2020

Usefulness of immunohistochemical staining for p53 in the prognosis of breast carcinomas: correlations with established prognosis parameters and with the proliferation marker, MIB-1

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12 December 2020

Expression of MAGE-antigens in normal tissues and cancer

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12 December 2020

Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray

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12 December 2020

Increased copy number at 20q13 in breast cancer: defining the critical region and exclusion of candidate genes

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12 December 2020

Messenger RNA determination of estrogen receptor, progesterone receptor, pS2, and plasminogen activator inhibitor-1 by competitive reverse transcription-polymerase chain reaction in human breast cancer

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12 December 2020

An immunomagnetic separation method using superparamagnetic (MACS) beads for large-scale purification of human mammary luminal and myoepithelial cells

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12 December 2020

Mammary gland development is mediated by both stromal and epithelial progesterone receptors

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12 December 2020

Localization and expression of p27KIP1 in multistage colorectal carcinogenesis

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12 December 2020

MAGE-A gene expression pattern in primary breast cancer

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6604181

1 reference

Dimensions Publication ID

1022461021

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1 reference

1 reference

PubMed publication ID

18195709

1 reference