Receptors for acylethanolamides-GPR55 and GPR119 (Q24647538)

Prostaglandins and Other Lipid Mediators

Europe PubMed Central

title

Receptors for acylethanolamides-GPR55 and GPR119 (English)

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Grzegorz Godlewski

1

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László Offertáler

series ordinal

2

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Jens A Wagner

series ordinal

3

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George Kunos

series ordinal

4

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language of work or name

English

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publication date

September 2009

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published in

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volume

89

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issue

3-4

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page(s)

105-11

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cites work

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Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells

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GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

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Novel cannabinoid receptors

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The orphan receptor GPR55 is a novel cannabinoid receptor

7 April 2017

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The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects

7 April 2017

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7 April 2017

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N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties

7 April 2017

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Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha

7 April 2017

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Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors

7 April 2017

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Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain

7 April 2017

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GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis

7 April 2017

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The enigmatic pharmacology of GPR55

7 April 2017

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2-Arachidonoyl-sn-glycero-3-phosphoinositol: a possible natural ligand for GPR55

7 April 2017

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Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119

7 April 2017

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The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

7 April 2017

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Identification of GPR55 as a lysophosphatidylinositol receptor

7 April 2017

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Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

7 April 2017

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In silico patent searching reveals a new cannabinoid receptor

7 April 2017

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Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor

7 April 2017

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Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives

7 April 2017

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Identification of G protein-coupled receptor genes from the human genome sequence

7 April 2017

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Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor

7 April 2017

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Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

7 April 2017

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Molecular characterization of a peripheral receptor for cannabinoids

7 April 2017

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Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

7 April 2017

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2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

7 April 2017

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Structure of a cannabinoid receptor and functional expression of the cloned cDNA

7 April 2017

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Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats

7 April 2017

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Isolation and structure of a brain constituent that binds to the cannabinoid receptor

7 April 2017

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Formation and inactivation of endogenous cannabinoid anandamide in central neurons

7 April 2017

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Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Glucose sensing in L cells: a primary cell study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

The endogenous brain constituent N-arachidonoyl L-serine is an activator of large conductance Ca2+-activated K+ channels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

The lipid messenger OEA links dietary fat intake to satiety.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

2-Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal-cannabidiol-sensitive receptors on microglial cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: evidence for a site distinct from CB1 and CB2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Expression and distribution of Gpr119 in the pancreatic islets of mice and rats: predominant localization in pancreatic polypeptide-secreting PP-cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Cellular and molecular biology of orphan G protein-coupled receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Cannabinoid receptor homo- and heterodimerization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Evidence for novel cannabinoid receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

The complexities of the cardiovascular actions of cannabinoids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Nonpsychotropic cannabinoid receptors regulate microglial cell migration.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

EDHF: bringing the concepts together

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Biological activities and metabolism of the lysophosphoinositides and glycerophosphoinositols.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

The palmitoylethanolamide family: a new class of anti-inflammatory agents?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

GPR55 and the vascular receptors for cannabinoids

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilatator responses in rat isolated hearts.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

The identification of peroxisome proliferator-activated receptor alpha-independent effects of oleoylethanolamide on intestinal transit in mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Oleoylethanolamide exerts partial and dose-dependent neuroprotection of substantia nigra dopamine neurons.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like Peptide-1 and glucose-dependent insulinotropic Peptide release

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Identification of the vasodilatory endothelial cannabinoid receptor in the human pulmonary artery.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Cannabinoid modulation of Kaposi's sarcoma-associated herpesvirus infection and transformation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Analgesic properties of oleoylethanolamide (OEA) in visceral and inflammatory pain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Atypical cannabinoid stimulates endothelial cell migration via a Gi/Go-coupled receptor distinct from CB1, CB2 or EDG-1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

Mesenteric vasodilation mediated by endothelial anandamide receptors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751869

2-Arachidonylglyceryl ether and abnormal cannabidiol-induced vascular smooth muscle relaxation in rabbit pulmonary arteries via receptor-pertussis toxin sensitive G proteins-ERK1/2 signaling

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19615459

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19615459

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

GPR55 as a new cannabinoid receptor: still a long way to prove it

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19615459

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.PROSTAGLANDINS.2009.07.001

1 reference

2074228

2074228

1 reference

1 reference

1 reference