Somatic mutations affect key pathways in lung adenocarcinoma (Q24648102)

85

0 references

William Pao

82

0 references

Carrie Sougnez

7

0 references

Lucinda Fulton

11

0 references

Marc Ladanyi

78

0 references

Elaine Mardis

4

0 references

Aleksandar Milosavljevic

33

0 references

Kristian Cibulskis

6

0 references

Gad Getz

2

0 references

Wendy Winckler

54

0 references

Heidi Greulich

8

0 references

Jennifer Baldwin

55

0 references

Liuda Ziaugra

66

0 references

Amit Dutt

57

0 references

Andrew C. Chang

75

0 references

Thomas Giordano

68

0 references

George Weinstock

George M Weinstock

84

0 references

Matthew Meyerson

89

Matthew Meyerson

0 references

Stacey Gabriel

86

Stacey B Gabriel

0 references

Ignacio I Wistuba

72

Ignacio I Wistuba

0 references

Michael A Province

83

Michael A Province

0 references

Michael C. Zody

67

Michael C Zody

0 references

Barbara A Weir

64

Barbara A Weir

0 references

Donna Muzny

9

Donna M Muzny

0 references

Michael D McLellan

5

Michael D McLellan

0 references

Qunyuan Zhang

13

Qunyuan Zhang

0 references

Aldi Kraja

48

Aldi Kraja

0 references

Lucian R Chirieac

56

Lucian R Chirieac

0 references

Hanna Wallach

59

Megan Hanna

0 references

Mark B. Orringer

69

Mark B Orringer

0 references

Jack A Roth

70

Jack A Roth

0 references

Margaret Spitz

71

Margaret R Spitz

0 references

David G Beer

76

David G Beer

0 references

Akihiko Yoshizawa

80

Akihiko Yoshizawa

0 references

Richard A Gibbs

88

Richard A Gibbs

0 references

David A. Wheeler

3

David A Wheeler

0 references

Richard K. Wilson

90

Richard K Wilson

0 references

Lora Lewis

23

Lora R Lewis

0 references

Margaret B Morgan

10

Margaret B Morgan

0 references

Shalini Jhangiani

22

Shalini N Jhangiani

0 references

Dan Koboldt

39

Daniel C Koboldt

0 references

Tracie L. Miner

42

Tracie L Miner

0 references

Heather Schmidt

46

Heather Schmidt

0 references

Craig S. Pohl

43

Craig Pohl

0 references

Ginger A. Fewell

44

Ginger Fewell

0 references

Aniko Sabo

19

Aniko Sabo

0 references

Alicia Hawes

20

Alicia C Hawes

0 references

Yanru Ren

27

Yanru Ren

0 references

David Dooling

18

David J Dooling

0 references

Tammi L Vickery

51

Tammi Vickery

0 references

Jody S Robinson

53

Jody Robinson

0 references

Xiaoqi Shi

37

Xiaoqi Shi

0 references

Yuzhu Tang

38

Yuzhu Tang

0 references

Carrie Haipek

45

Carrie Haipek

0 references

Brian H Dunford-Shore

47

Brian H Dunford-Shore

0 references

author name string

Li Ding

1

0 references

Robert S Fulton

12

0 references

Michael C Wendl

14

0 references

Michael S Lawrence

15

0 references

David E Larson

16

0 references

Ken Chen

17

0 references

Hua Shen

21

0 references

Otis Hall

24

0 references

Yiming Zhu

25

0 references

Tittu Mathew

26

0 references

Jiqiang Yao

28

0 references

Steven E Scherer

29

0 references

Kerstin Clerc

30

0 references

Ginger A Metcalf

31

0 references

Brian Ng

32

0 references

Manuel L Gonzalez-Garay

34

0 references

John R Osborne

35

0 references

Rick Meyer

36

0 references

Ling Lin

40

0 references

Rachel Abbott

41

0 references

Seth D Crosby

49

0 references

Christopher S Sawyer

50

0 references

Sacha Sander

52

0 references

Tim Fennell

58

0 references

Bruce E Johnson

60

0 references

Robert C Onofrio

61

0 references

Roman K Thomas

62

0 references

Giovanni Tonon

63

0 references

Xiaojun Zhao

65

0 references

Bradley Ozenberger

73

0 references

Peter J Good

74

0 references

Mark A Watson

77

0 references

Stephen Broderick

79

0 references

William D Travis

Characterizing the cancer genome in lung adenocarcinoma

81

0 references

language of work or name

English

0 references

publication date

23 October 2008

0 references

published in

Nature

0 references

volume

455

0 references

page(s)

1069-75

0 references

issue

7216

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

The genomic landscapes of human breast and colorectal cancers

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

The consensus coding sequences of human breast and colorectal cancers

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Global cancer statistics, 2002

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Mutations of the BRAF gene in human cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Lung cancer in never smokers: a review

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

The 2004 World Health Organization classification of lung tumors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Tobacco smoke carcinogens and lung cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Mutation analysis of the PTEN/MMAC1 gene in lung cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Patterns of somatic mutation in human cancer genomes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Mendelian Inheritance in Man and its online version, OMIM

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Adjuvant treatment in non-small cell lung cancer: Where are we now?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Somatic mutations of the protein kinase gene family in human lung cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Lung cancer: intragenic ERBB2 kinase mutations in tumours

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Role of DNA-PK in the cellular response to DNA double-strand breaks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Homozygous deletions at chromosome 9p21 and mutation analysis of p16 and p15 in microdissected primary non-small cell lung cancers.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

p53: a frequent target for genetic abnormalities in lung cancer.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Oncoproteins encoded by the cancer-associated human papillomaviruses target the products of the retinoblastoma and p53 tumor suppressor genes.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Genetic polymorphisms of ataxia telangiectasia mutated affect lung cancer risk.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

APC mutations are infrequent but present in human lung cancer.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2694412

Nras and Kras mutation in Japanese lung cancer patients: Genotyping analysis using LightCycler

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18948947

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for mendelian inheritance in the pathogenesis of lung cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18948947

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Environmental factors can confound identification of a major gene effect: results from a segregation analysis of a simulated population of lung cancer families

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18948947

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE07423

1 reference

Dimensions Publication ID

455578

1044282578

0 references

455578

1 reference

1 reference

1 reference