High-affinity blockade of voltage-operated skeletal muscle and neuronal sodium channels by halogenated propofol analogues (Q24649751)

2

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N Foadi

3

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S Gudehus

4

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A Roeder

5

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H Hecker

6

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R Dengler

7

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M Leuwer

British Journal of Pharmacology

8

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language of work or name

English

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publication date

September 2008

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published in

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volume

155

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issue

2

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page(s)

265-75

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cites work

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Structural requirements for voltage-dependent block of muscle sodium channels by phenol derivatives

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State-dependent block of voltage-gated Na+ channels by amitriptyline via the local anesthetic receptor and its implication for neuropathic pain

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28 September 2017

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An improved model for the binding of lidocaine and structurally related local anaesthetics to fast-inactivated voltage-operated sodium channels, showing evidence of cooperativity

28 September 2017

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High-affinity block of voltage-operated rat IIA neuronal sodium channels by 2,6 di-tert-butylphenol, a propofol analogue

28 September 2017

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Block of voltage-operated sodium channels by 2,6-dimethylphenol, a structural analogue of lidocaine's aromatic tail

28 September 2017

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Structural requirements of phenol derivatives for direct activation of chloride currents via GABA(A) receptors

28 September 2017

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General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility

28 September 2017

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Effect of drugs used for neuropathic pain management on tetrodotoxin-resistant Na(+) currents in rat sensory neurons

28 September 2017

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The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channels

28 September 2017

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Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors

28 September 2017

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Two human paramyotonia congenita mutations have opposite effects on lidocaine block of Na+ channels expressed in a mammalian cell line

28 September 2017

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Comparison of heterologously expressed human cardiac and skeletal muscle sodium channels

28 September 2017

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Functional consequences of lidocaine binding to slow-inactivated sodium channels

28 September 2017

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Dissecting lidocaine action: diethylamide and phenol mimic separate modes of lidocaine block of sodium channels from heart and skeletal muscle

28 September 2017

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Kinetic characterization of rat brain type IIA sodium channel alpha-subunit stably expressed in a somatic cell line

28 September 2017

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Functional expression and properties of the human skeletal muscle sodium channel

28 September 2017

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K(+)-aggravated myotonia: destabilization of the inactivated state of the human muscle Na+ channel by the V1589M mutation

28 September 2017

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Commentary: A revised view of local anesthetic action: what channel state is really stabilized?

28 September 2017

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Cocaine depresses GABAA current of hippocampal neurons

30 May 2018

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External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels.

30 May 2018

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Lidocaine block of cardiac sodium channels

30 May 2018

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Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction

30 May 2018

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30 May 2018

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Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine

28 November 2018

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Modeling of benzocaine analog interactions with the D4S6 segment of NaV4.1 voltage-gated sodium channels

28 November 2018

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General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.

28 November 2018

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Propofol blocks human skeletal muscle sodium channels in a voltage-dependent manner

28 November 2018

1 reference

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The alpha and gamma subunit-dependent effects of local anesthetics on recombinant GABA(A) receptors

28 November 2018

1 reference

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Succinylcholine metabolite succinic acid alters steady state activation in muscle sodium channels.

28 November 2018

1 reference

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Local anesthetics reduce the inhibitory neurotransmitter-induced current in dissociated hippocampal neurons of the rat.

28 November 2018

1 reference

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The influence of potassium and chloride ions on the membrane potential of single muscle fibres

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18574460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/BJP.2008.255

1 reference

1 reference

1 reference

PubMed publication ID

18574460

1 reference