Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component (Q24650458)

4

Robin J Shattock

0 references

Jon C. Mirsalis

7

Jon Mirsalis

0 references

Barry R O'Keefe

1

Barry R O'Keefe

0 references

Fakhrieh Vojdani

2

Fakhrieh Vojdani

0 references

author name string

Viviana Buffa

3

0 references

James Bakke

6

0 references

Anna-Lisa d'Andrea

8

0 references

Steven D Hume

9

0 references

Barry Bratcher

10

0 references

Carrie J Saucedo

11

0 references

James B McMahon

12

0 references

Gregory P Pogue

13

0 references

Kenneth E Palmer

Proceedings of the National Academy of Sciences of the United States of America

14

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language of work or name

English

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publication date

14 April 2009

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published in

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volume

106

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issue

15

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page(s)

6099-104

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cites work

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1 reference

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Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide

7 April 2017

1 reference

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Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp

7 April 2017

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

7 April 2017

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Cyanovirin-N potently inhibits human immunodeficiency virus type 1 infection in cellular and cervical explant models

7 April 2017

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Tropism-independent protection of macaques against vaginal transmission of three SHIVs by the HIV-1 fusion inhibitor T-1249.

28 September 2017

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Plant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: safety and immunogenicity in a phase I clinical study

28 September 2017

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28 September 2017

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Cost-effective production of a vaginal protein microbicide to prevent HIV transmission.

28 September 2017

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Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission

28 September 2017

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Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.

28 September 2017

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Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa

28 September 2017

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Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.

28 September 2017

1 reference

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In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories

28 September 2017

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Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

28 September 2017

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The nonnucleoside reverse transcriptase inhibitor UC-781 inhibits human immunodeficiency virus type 1 infection of human cervical tissue and dissemination by migratory cells

28 September 2017

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Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

28 September 2017

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Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update

28 September 2017

1 reference

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Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue

28 September 2017

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Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides

28 September 2017

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Heterologous sequences greatly affect foreign gene expression in tobacco mosaic virus-based vectors

28 September 2017

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Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

30 May 2018

1 reference

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Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0901506106

Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0901506106

Transgenic plant production of Cyanovirin-N, an HIV microbicide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0901506106

Safety concerns for the potential use of cyanovirin-N as a microbicidal anti-HIV agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0901506106

Recombinant production of anti-HIV protein, griffithsin, by auto-induction in a fermentor culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0901506106

HIV-1 subtype A envelope variants from early in infection have variable sensitivity to neutralization and to inhibitors of viral entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0901506106

Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89.6P in macaques

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19332801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparison of vaginal tolerance tests of spermicidal preparations in rabbits and monkeys

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19332801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0901506106

1 reference

ADS bibcode

2009PNAS..106.6099O

0 references

1 reference

1 reference

PubMed publication ID

19332801

1 reference