A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence (Q24650591)

8

object named as

Andrew H-J Wang

0 references

Eric Oldfield

9

object named as

Eric Oldfield

0 references

author name string

Chia-I Liu

1

0 references

George Y Liu

2

0 references

Yongcheng Song

3

0 references

Fenglin Yin

4

0 references

Mary E Hensler

5

0 references

Wen-Yih Jeng

Staphyloxanthin plays a role in the fitness of Staphylococcus aureus and its ability to cope with oxidative stress

6

0 references

language of work or name

English

0 references

publication date

7 March 2008

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published in

Science

0 references

volume

319

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issue

5868

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page(s)

1391-4

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747771

Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747771

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

7 April 2017

1 reference

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Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747771

Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747771

alpha-Phosphonosulfonic acids: potent and selective inhibitors of squalene synthase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2747771

Invasive methicillin-resistant Staphylococcus aureus infections in the United States

7 April 2017

1 reference

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Lipid-lowering properties of TAK-475, a squalene synthase inhibitor, in vivo and in vitro

7 April 2017

1 reference

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Bacterial virulence as a target for antimicrobial chemotherapy

28 September 2017

1 reference

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Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC

28 September 2017

1 reference

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Anchor structure of staphylococcal surface proteins. IV. Inhibitors of the cell wall sorting reaction

28 September 2017

1 reference

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Estimation of oral bioavailability of a long half-life drug in healthy subjects

30 May 2018

1 reference

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Antimicrobial resistance: it's not just for hospitals

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1153018

Syntheses and biological evaluation of novel quinuclidine derivatives as squalene synthase inhibitors

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1153018

Clinical pharmacokinetics and pharmacodynamics of a new squalene synthase inhibitor, BMS-188494, in healthy volunteers

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18276850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of ER-27856, a novel squalene synthase inhibitor, on plasma cholesterol in rhesus monkeys: comparison with 3-hydroxy-3-methylglutaryl-coa reductase inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18276850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1153018

1 reference

1 reference

1 reference

PubMed publication ID

18276850

1 reference