Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects (Q24652462)

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Inhibition of Schistosoma mansoni Thioredoxin-glutathione Reductase by Auranofin: STRUCTURAL AND KINETIC ASPECTS

Language	Label	Description	Also known as
English	Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects	scientific article	Inhibition of Schistosoma mansoni Thioredoxin-glutathione Reductase by Auranofin: STRUCTURAL AND KINETIC ASPECTS

Statements

scholarly article

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Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects (English)

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Schistosoma mansoni

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Maurizio Brunori

5

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Adriana E. Miele

object named as

Adriana E Miele

7

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author name string

Francesco Angelucci

1

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Ahmed A Sayed

2

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David L Williams

3

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Giovanna Boumis

4

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Daniela Dimastrogiovanni

6

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Frida Pauly

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Andrea Bellelli

9

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language of work or name

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publication date

16 October 2009

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Journal of Biological Chemistry

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284

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42

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28977-85

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Identification of oxadiazoles as new drug leads for the control of schistosomiasis

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7 April 2017

Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase

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Pushing the boundaries of molecular replacement with maximum likelihood

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Efficient anisotropic refinement of macromolecular structures using FFT

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7 April 2017

Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade

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7 April 2017

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

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7 April 2017

Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase

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7 April 2017

Gold-based therapeutic agents

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7 April 2017

Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems

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7 April 2017

Control of neglected tropical diseases

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7 April 2017

No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue

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28 September 2017

Focus on mammalian thioredoxin reductases--important selenoproteins with versatile functions

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28 September 2017

A sugar-modified phosphole gold complex with antiproliferative properties acting as a thioredoxin reductase inhibitor in MCF-7 cells

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28 September 2017

Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione.

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28 September 2017

New uses for old drugs

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28 September 2017

Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases

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28 September 2017

Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism

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28 September 2017

Linked thioredoxin-glutathione systems in platyhelminths

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28 September 2017

Resistance of Schistosoma mansoni to praziquantel: is there a problem?

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28 September 2017

The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase

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28 September 2017

Thioredoxin reductase as a pathophysiological factor and drug target

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28 September 2017

Alternative routes for entry of HgX2 into the active site of mercuric ion reductase depend on the nature of the X ligands

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28 September 2017

Will new antischistosomal drugs finally emerge?

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21 January 2018

Comparative modeling of thioredoxin glutathione reductase from Schistosoma mansoni: a multifunctional target for antischistosomal therapy

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https://api.crossref.org/works/10.1074%2FJBC.M109.020701

21 January 2018

New drugs for an ancient parasite

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21 January 2018

Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci).

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21 January 2018

Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds

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https://api.crossref.org/works/10.1074%2FJBC.M109.020701

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

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https://api.crossref.org/works/10.1074%2FJBC.M109.020701

21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

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21 January 2018

Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.

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https://api.crossref.org/works/10.1074%2FJBC.M109.020701

21 January 2018

The anti-schistosomal drug praziquantel is an adenosine antagonist

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21 January 2018

Gold(I) and Gold(0) Complexes of Phosphinine-Based Macrocycles

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19710012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiol competition for Et3PAuS-albumin: a nonenzymatic mechanism for Et3PO formation

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https://pubmed.ncbi.nlm.nih.gov/19710012

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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