Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities (Q24652603)

Christopher S Ward

4

0 references

Jeffrey L. Neul

Jeffrey L Neul

15

0 references

Huda Zoghbi

Huda Y Zoghbi

14

0 references

Alan K. Percy

12

Alan Percy

0 references

Daniel G Glaze

13

Daniel G Glaze

0 references

author name string

Caleigh Mandel-Brehm

2

0 references

Hsiao-Tuan Chao

3

0 references

Sharyl L Fyffe-Maricich

5

0 references

Jun Ren

6

0 references

Keith Hyland

7

0 references

Christina Thaller

8

0 references

Stephen M Maricich

9

0 references

Peter Humphreys

10

0 references

John J Greer

Proceedings of the National Academy of Sciences of the United States of America

11

0 references

language of work or name

English

0 references

publication date

22 December 2009

0 references

published in

0 references

volume

106

0 references

page(s)

21966-71

0 references

issue

51

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2799790/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Pathophysiology of locus ceruleus neurons in a mouse model of Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

MeCP2, a key contributor to neurological disease, activates and represses transcription

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

The history of dopamine and levodopa in the treatment of Parkinson's disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

The story of Rett syndrome: from clinic to neurobiology

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Defect in normal developmental increase of the brain biogenic amine concentrations in the mecp2-null mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Breathing disorders in Rett syndrome: progressive neurochemical dysfunction in the respiratory network after birth

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

The hyperactive syndrome: metanalysis of genetic alterations, pharmacological treatments and brain lesions which increase locomotor activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

From gene to aggressive behavior: the role of brain serotonin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Specific mutations in methyl-CpG-binding protein 2 confer different severity in Rett syndrome.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Investigating genotype-phenotype relationships in Rett syndrome using an international data set.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Clinical utility of monoamine neurotransmitter metabolite analysis in cerebrospinal fluid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Very mild cases of Rett syndrome with skewed X inactivation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

A genetic approach to access serotonin neurons for in vivo and in vitro studies.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

A method for automated detection of gene expression required for the establishment of a digital transcriptome-wide gene expression atlas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

X-Chromosome inactivation ratios affect wild-type MeCP2 expression within mosaic Rett syndrome and Mecp2-/+ mouse brain.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

The serotonergic system and anxiety

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Pathophysiology of Rett syndrome from the stand point of clinical characteristics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

The spectrum of behaviors influenced by serotonin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Cerebrospinal fluid biogenic amines and biopterin in Rett syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Rett syndrome--an early catecholamine and indolamine deficient disorder?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Cerebrospinal fluid values for monoamine metabolites, gamma-aminobutyric acid, and other amino compounds in Rett syndrome.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Reduction of biogenic amine levels in the Rett syndrome

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Evaluation of CSF neurotransmitters and folate in 25 patients with Rett disorder and effects of treatment

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912257106

Transgenic expression of Cre recombinase from the tyrosine hydroxylase locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912257106

Behaviour in the elevated plus-maze predicts coping after subchronic mild stress in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912257106

Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912257106

Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912257106

Evidence for both neuronal cell autonomous and nonautonomous effects of methyl-CpG-binding protein 2 in the cerebral cortex of female mice with Mecp2 mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912257106

Movement disorders in Rett syndrome: An analysis of 60 patients with detected MECP2 mutation and correlation with mutation type

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912257106

CSF and urine biogenic amine metabolites in Rett syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799790

Neuropathology of Rett syndrome

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20007372

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0912257106

1 reference

636239

ADS bibcode

2009PNAS..10621966S

0 references

636239

1 reference

1 reference

1 reference