Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake (Q24654300)

1

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Dineke E Folmer

2

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Helga E M Malingré

3

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Ellen van Beurden

4

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Adriana E M Klomp

5

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Bart van de Sluis

6

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Maarten Merkx

7

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Ruud Berger

8

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Leo W J Klomp

Characterization of COMMD protein-protein interactions in NF-kappaB signalling

9

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language of work or name

English

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publication date

1 October 2007

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published in

Biochemical Journal

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volume

407

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issue

1

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page(s)

49-59

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cites work

1 reference

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Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture

7 April 2017

1 reference

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Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane

7 April 2017

1 reference

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The N-terminus of the human copper transporter 1 (hCTR1) is localized extracellularly, and interacts with itself

7 April 2017

1 reference

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Biochemical characterization and subcellular localization of human copper transporter 1 (hCTR1)

7 April 2017

1 reference

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Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis

7 April 2017

1 reference

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The copper chaperone CCS directly interacts with copper/zinc superoxide dismutase

7 April 2017

1 reference

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hCTR1: a human gene for copper uptake identified by complementation in yeast

7 April 2017

1 reference

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Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking

7 April 2017

1 reference

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Biochemical characterization and intracellular localization of the Menkes disease protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Stable plasma membrane levels of hCTR1 mediate cellular copper uptake

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

The SLC31 (Ctr) copper transporter family

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Dynamic Traffic through the Recycling Compartment Couples the Metal Transporter Nramp2 (DMT1) with the Transferrin Receptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport system

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Molecular characterization of hCTR1, the human copper uptake protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Biochemical characterization of the human copper transporter Ctr1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

The copper transporter CTR1 provides an essential function in mammalian embryonic development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Isolation of a partial candidate gene for Menkes disease by positional cloning

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

A selective turn-on fluorescent sensor for imaging copper in living cells.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Copper transport protein (Ctr1) levels in mice are tissue specific and dependent on copper status

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

The many faces of the copper metabolism protein MURR1/COMMD1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Zinc-stimulated endocytosis controls activity of the mouse ZIP1 and ZIP3 zinc uptake transporters.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Ctr6, a vacuolar membrane copper transporter in Schizosaccharomyces pombe

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Molecular mechanisms of copper uptake and distribution

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Delivering copper within plant cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

A delicate balance: homeostatic control of copper uptake and distribution

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Intracellular pathways of copper trafficking in yeast and humans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Reduced stress defense in heme oxygenase 1-deficient cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Lysosomal Defect of Hepatic Copper Excretion in Wilson's Disease (Hepatolenticular Degeneration)

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Atp7a determines a hierarchy of copper metabolism essential for notochord development

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

The mechanism of copper uptake mediated by human CTR1: a mutational analysis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Mobilization of intracellular copper stores by the ctr2 vacuolar copper transporter

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Development of a hypoxia-responsive vector for tumor-specific gene therapy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Biliary excretion of copper in LEC rat after introduction of copper transporting P-type ATPase, ATP7B.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

A widespread transposable element masks expression of a yeast copper transport gene.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267400

Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17617060

12 December 2020

inferred from PubMed ID database lookup

Structure of the Ctr1 copper trans'PORE'ter reveals novel architecture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17617060

12 December 2020

inferred from PubMed ID database lookup

Pathobiology of copper-induced injury in Bedlington terriers: ultrastructural and microanalytical studies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17617060

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1042/BJ20070705

0 references

Fatcat ID

release_3srmbzc2cjatdcr7emv6oh4tky

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3srmbzc2cjatdcr7emv6oh4tky

24 November 2022