Effects of NXY-059 in experimental stroke: an individual animal meta-analysis (Q24654761)

ORCID Public Data File 2021

author name string

P M W Bath

1

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L J Gray

2

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A J G Bath

3

0 references

T Miyata

5

0 references

A R Green

British Journal of Pharmacology

6

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language of work or name

English

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publication date

August 2009

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published in

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volume

157

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issue

7

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page(s)

1157-71

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cites work

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NXY-059, a free radical--trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species

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Effect of NXY-059 on secondary mitochondrial dysfunction after transient focal ischemia; comparison with cyclosporin A.

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A novel inhibitor of advanced glycation and endoplasmic reticulum stress reduces infarct volume in rat focal cerebral ischemia

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Pharmacokinetics of NXY-059, a nitrone-based free radical trapping agent, in healthy young and elderly subjects

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Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial

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Brain penetration of the novel free radical trapping neuroprotectant NXY-059 in rats subjected to permanent focal ischemia

28 November 2018

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Coadministration of NXY-059 and tenecteplase six hours following embolic strokes in rabbits improves clinical rating scores

28 November 2018

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NXY-059, a nitrone with free radical trapping properties inhibits release of cytochrome c after focal cerebral ischemia.

28 November 2018

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Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion

28 November 2018

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Tolerability of NXY-059 at higher target concentrations in patients with acute stroke

28 November 2018

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NXY-059 maintains Akt activation and inhibits release of cytochrome C after focal cerebral ischemia.

28 November 2018

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Effects of the spin trap agent disodium- [tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit Large clot embolic stroke model: combination studies with tissue plasminogen activator

28 November 2018

1 reference

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Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743834

NXY-059 for the treatment of acute ischemic stroke

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19422398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Can We Improve the Statistical Analysis of Stroke Trials?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19422398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2009.00196.X

1 reference

1 reference

1 reference

PubMed publication ID

19422398

1 reference