An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli (Q24654765)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1901760

beta-L-Ara4N-lipid A metabolic process

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1901759

UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity

1 reference

Gene Ontology release 2020-05-02

Aixin Yan

1

0 references

Ziqiang Guan

series ordinal

2

0 references

Christian R H Raetz

series ordinal

3

0 references

language of work or name

English

0 references

publication date

7 December 2007

0 references

published in

Journal of Biological Chemistry

0 references

volume

282

0 references

issue

49

0 references

page(s)

36077-89

0 references

cites work

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Structure and mechanism of ArnA: conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistance

7 April 2017

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Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis

7 April 2017

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Plaque formation and isolation of pure lines with poliomyelitis viruses

7 April 2017

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Lipopolysaccharide endotoxins

7 April 2017

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The pleiotropic two-component regulatory system PhoP-PhoQ

7 April 2017

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Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

7 April 2017

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An O-antigen processing function for Wzx (RfbX): a promising candidate for O-unit flippase

7 April 2017

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Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

7 April 2017

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Rapid transmembrane movement of newly synthesized phospholipids during membrane assembly

7 April 2017

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

7 April 2017

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Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme

7 April 2017

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Pathogen recognition and innate immunity

7 April 2017

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Innate immune recognition

7 April 2017

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The complete genome sequence of Escherichia coli K-12

7 April 2017

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The multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily

7 April 2017

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Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein

7 April 2017

1 reference

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Two distinct but interchangeable mechanisms for flipping of lipid-linked oligosaccharides

7 April 2017

1 reference

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An Escherichia coli mutant defective in lipid export

7 April 2017

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Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria

7 April 2017

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The activity of a putative polyisoprenol-linked sugar translocase (Wzx) involved in Escherichia coli O antigen assembly is independent of the chemical structure of the O repeat

7 April 2017

1 reference

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Intracellular functions of N-linked glycans

7 April 2017

1 reference

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An efficient recombination system for chromosome engineering in Escherichia coli

7 April 2017

1 reference

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Molecular basis of bacterial outer membrane permeability

7 April 2017

1 reference

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High efficiency transformation of Escherichia coli with plasmids

7 April 2017

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Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli

7 April 2017

1 reference

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When biochemistry meets structural biology: the cautionary tale of EmrE.

7 April 2017

1 reference

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Structure and function of Toll receptors and their ligands

28 September 2017

1 reference

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Lipidomic strategies to study structural and functional defects of ABC-transporters in cellular lipid trafficking

28 September 2017

1 reference

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Comparison of three structures of the multidrug transporter EmrE.

28 September 2017

1 reference

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An outer membrane enzyme encoded by Salmonella typhimurium lpxR that removes the 3'-acyloxyacyl moiety of lipid A.

28 September 2017

1 reference

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Dodecaprenyl phosphate-galacturonic acid as a donor substrate for lipopolysaccharide core glycosylation in Rhizobium leguminosarum

28 September 2017

1 reference

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RETRACTED: X-ray structure of the EmrE multidrug transporter in complex with a substrate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613183

Global topology analysis of the Escherichia coli inner membrane proteome

28 September 2017

1 reference

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A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose

28 September 2017

1 reference

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Role of Mg2+ and pH in the modification of Salmonella lipid A after endocytosis by macrophage tumour cells.

28 September 2017

1 reference

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Phenotypic differences between Salmonella and Escherichia coli resulting from the disparate regulation of homologous genes

28 September 2017

1 reference

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MsbA transporter-dependent lipid A 1-dephosphorylation on the periplasmic surface of the inner membrane: topography of francisella novicida LpxE expressed in Escherichia coli

28 September 2017

1 reference

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MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli

28 September 2017

1 reference

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The PmrA-regulated pmrC gene mediates phosphoethanolamine modification of lipid A and polymyxin resistance in Salmonella enterica

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613183

Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli

28 September 2017

1 reference

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Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2613183

Innate immune sensing and its roots: the story of endotoxin

28 September 2017

1 reference

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Contributions of MexAB-OprM and an EmrE homolog to intrinsic resistance of Pseudomonas aeruginosa to aminoglycosides and dyes

28 September 2017

1 reference

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Substrate analogues to study cell-wall biosynthesis and its inhibition

28 September 2017

1 reference

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N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli

28 September 2017

1 reference

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Mammalian ABC transporters in health and disease

28 September 2017

1 reference

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Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose

28 September 2017

1 reference

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Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli: structural characterization and transfer to lipid A in the periplasm

28 September 2017

1 reference

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An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donor

28 September 2017

1 reference

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Lipid A modifications in polymyxin-resistant Salmonella typhimurium: PMRA-dependent 4-amino-4-deoxy-L-arabinose, and phosphoethanolamine incorporation

28 September 2017

1 reference

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SMR-type multidrug resistance pumps.

28 September 2017

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Salmonella: a model for bacterial pathogenesis.

28 September 2017

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A PhoP/PhoQ-induced Lipase (PagL) that catalyzes 3-O-deacylation of lipid A precursors in membranes of Salmonella typhimurium

28 September 2017

1 reference

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Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimurium

28 September 2017

1 reference

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Oxygen requirement for the biosynthesis of the S-2-hydroxymyristate moiety in Salmonella typhimurium lipid A. Function of LpxO, A new Fe2+/alpha-ketoglutarate-dependent dioxygenase homologue

28 September 2017

1 reference

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Regulation of blood coagulation

28 September 2017

1 reference

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Lipid A modifications characteristic of Salmonella typhimurium are induced by NH4VO3 in Escherichia coli K12. Detection of 4-amino-4-deoxy-L-arabinose, phosphoethanolamine and palmitate

28 September 2017

1 reference

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Regulation of polymyxin resistance and adaptation to low-Mg2+ environments

28 September 2017

1 reference

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Regulation of lipid A modifications by Salmonella typhimurium virulence genes phoP-phoQ.

28 September 2017

1 reference

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PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance

28 September 2017

1 reference

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The SMR family: a novel family of multidrug efflux proteins involved with the efflux of lipophilic drugs.

28 September 2017

1 reference

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Spontaneous pmrA mutants of Salmonella typhimurium LT2 define a new two-component regulatory system with a possible role in virulence

28 September 2017

1 reference

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Inside-outside transitions of phospholipids in vesicle membranes

28 September 2017

1 reference

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Agents that increase the permeability of the outer membrane.

28 September 2017

1 reference

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A rapid and simple method for inactivating chromosomal genes in Yersinia

28 September 2017

1 reference

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Bacterial polysaccharide synthesis and gene nomenclature

28 September 2017

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Experimentally constrained topology models for 51,208 bacterial inner membrane proteins

28 September 2017

1 reference

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High-resolution NMR spectroscopy of lipid A molecules containing 4-amino-4-deoxy-L-arabinose and phosphoethanolamine substituents. Different attachment sites on lipid A molecules from NH4VO3-treated Escherichia coli versus kdsA mutants of Salmonella

30 May 2018

1 reference

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PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance.

30 May 2018

1 reference

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Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR study.

30 May 2018

1 reference

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Lipopolysaccharides of polymyxin B-resistant mutants of Escherichia coli are extensively substituted by 2-aminoethyl pyrophosphate and contain aminoarabinose in lipid A.

30 May 2018

1 reference

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Characterization of the lipopolysaccharide from the polymyxin-resistantpmrAmutants ofSalmonella typhimurium

30 May 2018

1 reference

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Phosphatidyl-ethanolamine: Differential labelling in intact cells and cell ghosts of human erythrocytes by a membrane-impermeable reagent

30 May 2018

1 reference

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Location of polar substituents and fatty acyl chains on lipid A precursors from a 3-deoxy-D-manno-octulosonic acid-deficient mutant of Salmonella typhimurium. Studies by 1H, 13C, and 31P nuclear magnetic resonance

30 May 2018

1 reference

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30 May 2018

1 reference

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The Occurrence of 4-Amino-4-deoxy-l-arabinose as a Constituent in Salmonella Lipopolysaccharide Preparations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706172200

ATPase activity of the MsbA lipid flippase of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706172200

EmrE, a multidrug transporter from Escherichia coli, transports monovalent and divalent substrates with the same stoichiometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706172200

The reconstitution and activity of the small multidrug transporter EmrE is modulated by non-bilayer lipid composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706172200

Two oligosaccharyl transferase complexes exist in yeast and associate with two different translocons.

21 January 2018

1 reference

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Characterization of the lipid-carrier involved in the synthesis of enterobacterial common antigen (ECA) and identification of a novel phosphoglyceride in a mutant of Salmonella typhimurium defective in ECA synthesis.

21 January 2018

1 reference

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Evidence that the wzxE gene of Escherichia coli K-12 encodes a protein involved in the transbilayer movement of a trisaccharide-lipid intermediate in the assembly of enterobacterial common antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706172200

Emulating membrane protein evolution by rational design

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706172200

Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis

21 January 2018

1 reference

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Biochemical methods to determine cell-surface topography

28 November 2018

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12 December 2020

Transbilayer movement of dipalmitoylphosphatidylcholine in proteoliposomes reconstituted from detergent extracts of endoplasmic reticulum. Kinetics of transbilayer transport mediated by a single flippase and identification of protein fractions enric

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12 December 2020

Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli

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12 December 2020

Identification and evolution of dual-topology membrane proteins

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12 December 2020

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12 December 2020

Detergent-accelerated hydrolysis of bacterial endotoxins and determination of the anomeric configuration of the glycosyl phosphate present in the "isolated lipid A" fragment of the Bordetella pertussis endotoxin

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12 December 2020

pAM beta 1 resolvase has an atypical recombination site and requires a histone-like protein HU

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7 January 2021