MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2 (Q24655427)

6

object named as

Joseph Loscalzo

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author name string

Stephen Y Chan

1

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Ying-Yi Zhang

2

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Christopher E Mahoney

4

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Jay L Zweier

MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3

5

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language of work or name

English

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publication date

October 2009

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published in

Cell Metabolism

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volume

10

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page(s)

273-84

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issue

4

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cites work

1 reference

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HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

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A microRNA signature of hypoxia

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Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells

7 April 2017

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MicroRNA regulation of DNA repair gene expression in hypoxic stress

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

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Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice

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Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells

7 April 2017

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Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo

7 April 2017

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Hypoxia response and microRNAs: no longer two separate worlds.

28 September 2017

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PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis

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hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer

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Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

28 September 2017

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Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1.

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Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis

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Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.

28 September 2017

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VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.

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Hypoxic pulmonary vasoconstriction

28 November 2018

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28 November 2018

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DNA binding and dimerization of the Fe-S-containing FNR protein from Escherichia coli are regulated by oxygen.

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19808020

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2009.08.015

1 reference

869844

869844

1 reference

1 reference

1 reference